CASP4

CASP4, also known as caspase 4, belongs to the caspase family of cysteine proteases. It is also commonly referred to as ICH - 2 or TX. Its mechanism of action involves activation in response to various cellular stress signals. It participates in the inflammatory and apoptotic pathways, cleaving specific substrates to initiate programmed cell death and inflammation.
This protein is associated with multiple diseases, including neurodegenerative diseases and inflammatory disorders. Regarding drug development, research is underway to find inhibitors that can precisely target CASP4, aiming to modulate its activity and provide new treatment strategies for related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following CASP4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CASP4 Antibodies

CASP4 Proteins

CASP4 Antibodies

CASP4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA004549GA01HU	CASP4 Antibody	Human	ELISA,WB,IHC
CSB-PA000023	Cleaved-CASP4 (Q81) Antibody	Human	WB, IHC, ELISA
CSB-PA060272	Cleaved-CASP4/CASP5 (D270/D311) Antibody	Human	WB, ELISA
CSB-PA060273	CASP4 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA004549LA01HU	CASP4 Antibody	Human, Mouse	ELISA, WB, IHC, IF

CASP4 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA866914XA01DOA	CASP4 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

CASP4 Proteins

CASP4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP004549HU CSB-EP004549HU CSB-BP004549HU CSB-MP004549HU CSB-EP004549HU-B	Recombinant Human Caspase-4 (CASP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP004549HU(A4)	Recombinant Human Caspase-4 (CASP4)	E.coli

CASP4 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-CF866914DOA	Recombinant Arabidopsis thaliana Casparian strip membrane protein 4 (CASP4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP866914DOA1 CSB-EP866914DOA1 CSB-BP866914DOA1 CSB-MP866914DOA1 CSB-EP866914DOA1-B	Recombinant Arabidopsis thaliana Casparian strip membrane protein 4 (CASP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CASP4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP691616BO CSB-EP691616BO CSB-BP691616BO CSB-MP691616BO CSB-EP691616BO-B	Recombinant Bovine Caspase-4 (CASP4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CASP4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP004549MO CSB-EP004549MO CSB-BP004549MO CSB-MP004549MO CSB-EP004549MO-B	Recombinant Mouse Caspase-4 (Casp4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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CASP4

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