ANXA2

Annexin A2 (ANXA2) is a calcium-dependent phospholipid-binding protein. It is also known as lipocortin II or calpactin I heavy chain. ANXA2 binds to negatively charged phospholipids and plays a role in various cellular processes such as membrane trafficking, cell adhesion, and migration. It is involved in the MAPK and PI3K-Akt signaling pathways.
ANXA2 has been associated with multiple diseases, including cancer, where it promotes tumor progression and metastasis. In addition, it is related to cardiovascular and neurodegenerative diseases. Regarding drug development, ANXA2 is emerging as a promising target. Some small - molecule inhibitors are under pre - clinical investigation to block its function in disease pathways.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ANXA2 Recombinant Monoclonal Antibody(CSB-RA987782A0HU)

Validated Data

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, PC3 whole cell lysate
All lanes: ANXA2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39, 41 kDa
Observed band size: 36-45 kDa

IHC image of CSB-RA987782A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

Human Annexin Ⅱ(ANX-Ⅱ) ELISA Kit(CSB-E12156h)

Validated Data

Code: CSB-E12156h

Size: 96T,5×96T,10×96T

Sensitivity: 0.098 ng/mL

Detection Range: 0.39 ng/mL-25 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following ANXA2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ANXA2 Antibodies

ANXA2 Proteins

ANXA2 ELISA Kits

ANXA2 Antibodies

ANXA2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA01064D0Rb	ANXA2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA001840GA01HU	ANXA2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA01064A0Rb	ANXA2 Antibody	Human	ELISA, WB
CSB-PA001840HA01HU	ANXA2 Antibody	Human, Mouse	ELISA, WB, IHC, IF, IP
CSB-PA001840HD01HU	ANXA2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA548570	Phospho-ANXA2 (Ser26) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA000879	ANXA2 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA005132	ANXA2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA009119	Phospho-ANXA2 (S26) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA081479	ANXA2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA980450	ANXA2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-MA0106441A0m	ANXA2 Monoclonal Antibody	Human	ELISA,WB,IHC
CSB-RA987782A0HU	ANXA2 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

ANXA2 Proteins

ANXA2 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP001840DO CSB-EP001840DO CSB-BP001840DO CSB-MP001840DO CSB-EP001840DO-B	Recombinant Dog Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP001840SH CSB-EP001840SH CSB-BP001840SH CSB-MP001840SH CSB-EP001840SH-B	Recombinant Sheep Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP001840CH CSB-EP001840CH CSB-BP001840CH CSB-MP001840CH CSB-EP001840CH-B	Recombinant Chicken Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Cervus elaphus (Red deer)

Code	Product Name	Source
CSB-YP001840DRN CSB-EP001840DRN CSB-BP001840DRN CSB-MP001840DRN CSB-EP001840DRN-B	Recombinant Cervus elaphus Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP001840HU CSB-EP001840HU CSB-BP001840HU CSB-MP001840HU CSB-EP001840HU-B	Recombinant Human Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP001840HU	Recombinant Human Annexin A2 (ANXA2)	E.coli
CSB-MP001840HU	Recombinant Human Annexin A2 (ANXA2)	Mammalian cell
CSB-RP010644h	Recombinant Human Annexin A2 (ANXA2)	E.coli
CSB-EP001840HUa0	Recombinant Human Annexin A2 (ANXA2)	E.coli
CSB-EP001840HUb2	Recombinant Human Annexin A2 (ANXA2)	E.coli
CSB-EP001840HUe0	Recombinant Human Annexin A2 (ANXA2)	E.coli

ANXA2 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP001840PI CSB-EP001840PI CSB-BP001840PI CSB-MP001840PI CSB-EP001840PI-B	Recombinant Pig Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP001840PYX CSB-EP001840PYX CSB-BP001840PYX CSB-MP001840PYX CSB-EP001840PYX-B	Recombinant Pongo abelii Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP001840BO CSB-EP001840BO CSB-BP001840BO CSB-MP001840BO CSB-EP001840BO-B	Recombinant Bovine Annexin A2 (ANXA2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ANXA2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP001840MO CSB-EP001840MO CSB-BP001840MO CSB-MP001840MO CSB-EP001840MO-B	Recombinant Mouse Annexin A2 (Anxa2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP001840MO	Recombinant Mouse Annexin A2 (Anxa2)	Mammalian cell
CSB-EP001840MO	Recombinant Mouse Annexin A2 (Anxa2)	E.coli
CSB-YP001840MO	Recombinant Mouse Annexin A2 (Anxa2)	Yeast

ANXA2 ELISA Kit

ANXA2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E12156h	Human Annexin Ⅱ(ANX-Ⅱ) ELISA Kit	serum, urine, saliva, cell lysates	0.098 ng/mL

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ANXA2

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