Recombinant Chicken Proto-oncogene tyrosine-protein kinase ROS (ROS1), partial

Code
MSDS
Size Pls inquire
Source
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ROS1
Uniprot NO.
Species
Gallus gallus (Chicken)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Description

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Target Background

Function
Orphan receptor tyrosine kinase (RTK) that may activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1, and PLCG2.
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
Tissue Specificity
Highest expression in kidney. Also expressed in gonad, thymus, bursa, brain and kidney.
Database Links

UNIGENE: Gga.702

STRING: 9031.ENSGALP00000036566

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