ROS1 Antibody

Code: CSB-PA020072XA01CH

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Size:

0.1ml

0.1ml1ml

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Quantity:

Species Reactivity: Gallus gallus (Chicken)

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P08941

Target Names

ROS1

Alternative Names

ROS1 antibody; Proto-oncogene tyrosine-protein kinase ROS antibody; EC 2.7.10.1 antibody; Proto-oncogene c-Ros antibody; Proto-oncogene c-Ros-1 antibody; Receptor tyrosine kinase c-ros oncogene 1 antibody; c-Ros receptor tyrosine kinase antibody

Raised in

Rabbit

Species Reactivity

Gallus gallus (Chicken)

Immunogen

Recombinant Gallus gallus (Chicken) ROS1 protein

Immunogen Species

Gallus gallus (Chicken)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Orphan receptor tyrosine kinase (RTK) that may activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1, and PLCG2.

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily

Tissue Specificity

Highest expression in kidney. Also expressed in gonad, thymus, bursa, brain and kidney.

Database Links

UNIGENE: Gga.702

STRING: 9031.ENSGALP00000036566

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