DPEP3 (US10189910B2 Biosimilar) Recombinant Monoclonal Antibody

CSB-RA007125MB1HU
Size:
100ug
100ug500ug1mg5mg10mg50mg100mg200mg
US$199
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Species Reactivity: Human
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Product Details

Uniprot NO.
Alternative Names
Dipeptidase 3 antibody; DPEP3 antibody; UNQ834/PRO1772 antibody
Species Reactivity
Human
Immunogen
Recombinant Human DPEP3 protein
Conjugate
Non-conjugated
Clonality
Monoclonal
Buffer
0.01M PBS,pH7.4
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Concentration
It differs from different batches. Please contact us to confirm it.
Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.
Datasheet & COA
Description

This recombinant monoclonal antibody is developed as a research-grade biosimilar to the reference antibody described in patent US10189910B2, specifically targeting DPEP3 (Dipeptidase 3). DPEP3 is a membrane-bound metallopeptidase that catalyzes the hydrolysis of dipeptides and plays a role in cellular metabolism and peptide processing. This enzyme belongs to the dipeptidase family and is expressed in various tissues, where it participates in the final steps of protein degradation and amino acid recycling. DPEP3 has been implicated in metabolic processes and may have relevance in studies of cellular homeostasis and nutrient sensing pathways.

The reference antibody outlined in US10189910B2 provides a well-characterized framework for investigating DPEP3 expression and function in biological systems. This biosimilar antibody serves as a valuable research tool for scientists studying dipeptidase biology, metabolic regulation, and related cellular mechanisms. It enables researchers to explore DPEP3's role in various physiological and pathological contexts, supporting investigations into enzyme function and potential disease associations.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function
Dipeptidase that hydrolyzes cystinyl-bis-glycine. Does not hydrolyze leukotriene D4 (LTD4) into leukotriene E4 (LTE4).
Gene References into Functions
  1. This paper describes differences in substrate specificity and tissue distribution of membrane-bound dipeptidase 3 from mouse in comparison to other mouse members of this family. PMID:12738806

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Subcellular Location
Membrane; Lipid-anchor, GPI-anchor.
Protein Families
Metallo-dependent hydrolases superfamily, Peptidase M19 family
Database Links

HGNC: 23029

UNIGENE: Hs.302028

KEGG: hsa:64180

STRING: 9606.ENSP00000268793

OMIM: 609926

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