DWVIPPIIVSENEKGPFPKRIVQIKSSYAKEVKVYYSITGQGADTPPEGVFAIGREDGWLNVTRPLDREAIDNYVLFSHAVSSNGANVEDPMEIIIKVQDQNDNDPVFTQSVFEGSVPEGSKPGTAVMTVSATDADDSVDMYNGVITYSILNQEPKEPTNKMFTIHSESGLISVLTTGLDREKNPVYTLTIQAADGEFGKDRTTTATALIVVMDTNDNPPVFDPTQYTAKVPENEVGYEVARLTVTDEDIEGTDAWNAVYKIIKGNEANYFSIQTDTGNIGLLKTVKGLDYELKKQYILSVIVTNKANFSVPLQTSTATVTVSVEDVNEAPIFLPPVKEVSVSEDLPSGQVVATYTAQDPDKEQNQKITYVIGNDPAGWVSVNKDNGIVTGNGNLDRESKFVLNNTYKVIILAADSGSPSATGTGTLVLNLLDVNDNGPFLEPQQESFCQKDPGFRVFTIIDRDLSPNTYPYKAELTGESNENWTAIVTGQSILELRPKKELEIGQYDVMITLLDSFGLSNVTKLHITICQCDGDKMQCEEKAAIAGGLGISAIVGILGGILALLLLLLLLLLFVRRKKVVKEPLLPPEDETRDNVFSYDEEGGGEEDQDFDLSQLHRGLDARPDVIRNDVAPVLAAPQYRPRPANPDEIGNFIDENLNAADNDPTAPPYDSLLVFDYEGSGSEAASLSSLNSPNSDLDQDYSALNDWGPRFTKLADMYGGDED
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-cadherin is a ligand for integrin alpha-E/beta-7.
Gene References into Functions
JNK deficient embryos also have increased intercellular adhesion and defects in e-cadherin localization. Conversely, embryos with overactive JNK have epidermal fragility, increased E-cadherin internalization, and increased membrane localized clathrin.PMID:28032936
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Subcellular Location
Cell membrane; Single-pass type I membrane protein.