Recombinant Rat Syndecan-3 (Sdc3)

Code: CSB-CF020890RA

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20μg100μg

US$5473

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Express system: in vitro E.coli expression system

Species: Rattus norvegicus (Rat)

Tag Info: N-terminal 10xHis-tagged

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Target Background

Product Details

Target Names

Sdc3

Uniprot NO.

P33671

Species

Rattus norvegicus (Rat)

Source

in vitro E.coli expression system

Expression Region

45-442

Target Protein Sequence

AQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDIALAAPTAPAMLPTTVIQPVDTPFEELLSEHPGPEPVTSPPLVTEVTEVVEEPSQRATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPAAPPATATTADIRTTGIQGLLPLPLTTAATAKATTPAVPSPPTTVTTLDTEAPTPRLVNTATSRPRALPRPVTTQEPEVAERSTLPLGTTAPGPTEVAQTPTPESLLTTTQDEPEVPVSGGPSGDFELQEETTQPDTANEVVAVEGAAAKPSPPLGTLPKGARPGLGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

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Target Background

Function(From Uniprot)

Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.

Gene References into Functions

The mRNA expression of N-syndecan, a PTN receptor, was up-regulated in GalN-treated hepatocytes. PMID:12057922
Syndecan-3 is synthesized by oligodendrocyte progenitors (but not terminally differentiated oligodendrocytes) and is up-regulated by FGF-2. PMID:12210841

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

Syndecan proteoglycan family

Tissue Specificity

High levels in neonatal brain, heart, and Schwann cells, barely detectable in neonatal or adult liver, or adult brain.

Database Links

UNIGENE: Rn.10504

KEGG: rno:116673

STRING: 10116.ENSRNOP00000041634

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