Recombinant Rat C-X-C chemokine receptor type 2 (Cxcr2)

1. These data are concomitant with abnormal cerebral CXCL1/CXCR2 expression, and support temporal aberrations in CXCL1/CXCR2 and neutrophil dynamics in the placental-fetal-brain axis following chorioamnionitis PMID:29117499
2. The mRNA and protein levels of CXCR2 were significantly increased in the pulmonary tissue in a rat model of hepatopulmonary syndrome. PMID:27879294
3. Findings indicated that up-regulation of CXCL1 and CXCR2 might contribute to remifentanil-induce hypernociception via modulating spinal NR2B-containing NMDA receptor expression and phosphorylation in rats. PMID:26724371
4. GRK6 might be a key molecular involved in peripheral mechanism of neuropathic pain and that overexpression of GRK6 might be a potential strategy for treatment for neuropathic pain through inhibition of CXCR2 signal pathway. PMID:27145805
5. Findings indicate that acupuncture can increase the number of implanted embryos in embryo implantation failure, which may be relevant with up-regulation the expression of CXCL8 receptors CXCR1 and CXCR2 in endometrium. PMID:24496685
6. These data suggests an important role for CXCR2 receptors in oral squamous cell carcinoma. PMID:21670971
7. IL8RA-endothelial cells (EC), IL8RB-EC, and IL8RA/IL8RB-EC treatment reduces neointima formation dramatically in carotid artery endothelial cells at 28 days after injury. PMID:22361324
8. Inhibition of CXCR1 and CXCR2 chemokine receptors is an effective anti-inflammatory and neuroprotective treatment after spinal cord injury. PMID:20877331
9. These data suggest that CXCR2 overexpression in peripheral T cells is intracerebral microglial TNF-alpha-dependent and TNF-alpha primes T cells transendothelial migration in Alzheimer's diseases. PMID:18462836
10. data show that TII alveolar epithelial cells produce three of the major proinflammatory CXC chemokines (GRO, CINC-2alpha, and MIP-2) and their cognate receptor CXCR2 PMID:12829448
11. A specific CXCR2 antagonist, SB-332235, effectively inhibited cigarette smoke-induced neutrophilia in a dose-dependent manner. PMID:15516486
12. Neuronal CXCR2 immunoreactivity was detected in several brain areas, which rapidly but transiently downregulated upon trauma. PMID:16472549
13. These findings highlight the contribution of CXCR2 in the pathophysiology of adjuvant-induced polyarthritis (AIA) PMID:17891165
14. CXCR2 activation might directly contribute to motor neuron degeneration PMID:18391506
15. Results suggest that the CXCR2 and PI3Kgamma signaling pathway may represent a suitable target for the development of novel therapeutic strategies for human diseases characterized by vascular leakage. PMID:19255141

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UNIGENE: Rn.90347

KEGG: rno:29385

STRING: 10116.ENSRNOP00000019109