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Recombinant Pygathrix bieti C-C chemokine receptor type 5 (CCR5)

Recombinant Pygathrix bieti C-C chemokine receptor type 5 (CCR5)

CSB-CF004844FHN

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20μg100μg

US$5128

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Express system: in vitro E.coli expression system

Species: Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)

Tag Info: N-terminal 10xHis-tagged

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Product Details
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Target Background

Product Details

Target Names

CCR5

Uniprot NO.

O97880

Species

Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)

Source

in vitro E.coli expression system

Expression Region

1-352

Target Protein Sequence

MDYQVSSPTYDIDYYTSEPCQKVNVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKR LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII LLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSS HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV GEKFRNYLLVFFQKHIAKRFCKCCYIFQQEAPERASSVYTRSTGEQEISVGL

Protein Length

full length protein

Tag Info

N-terminal 10xHis-tagged

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Description

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Target Background

Function

Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family

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