LAEGVQCDLQPVDPKVTYTTSQVSEGCVAHVPNATVGVHILFLEFSKEVSTLELTVQMTNPNGARPQEVLLILSVNKNIHLTLQVPEIPLHLAYDSKLVFLQEAPKAVITELPPSTTKNQLFLWANTKGSIISAAELDNPQSILLRLDQAPTSPSRCTLEPRKDMGHTLEWKSHTQASVLGCHLEGVTGHKEAHILRVLPGSEAWPRTVTVEVELSCALRDPEAVLILQGPPYVSWLIDANHNVKAWTTGEYSFKIFPGSNIQGVNLPDTRQGLLEEARKLNASVIASFVELPLASVISLQDRSCGSGLQPSPTTVQITPPGEGCNQDLLLSLIQPRCSDDVMTLVLRKDLISTLGCTITSLTFWDPSCQAEDTDDKFVLRGTYSSCGMKVAENVVISNEVVVNLLSSSSPQRKQVQCINLDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPSIPELMTQLDSCQLNLGPDVEMVDLIQNQEAKSSCVSLLSPSPGGDMRFSFLLRGYVVPMPTAGILSCTVALRPRTWSLDVHKTASTRLNIVSPGLPDKGLVLPAVLGITFGAFLIGALLTAALWYIHSHTRHPGKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. May play a role in the binding of endothelial cells to integrins. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3.
Subcellular Location
Cell membrane; Single-pass type I membrane protein.