Recombinant Pig Calcitonin receptor (CALCR)

Code: CSB-CF004439PI

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20μg100μg

US$6004

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Express system: in vitro E.coli expression system

Species: Sus scrofa (Pig)

Tag Info: N-terminal 10xHis-tagged

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Product Details
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Target Background

Product Details

Target Names

CALCR

Uniprot NO.

P25117

Species

Sus scrofa (Pig)

Source

in vitro E.coli expression system

Expression Region

30-498

Target Protein Sequence

AHTPTLEPEPFLYILGKQRMLEAQHRCYDRMQKLPPYQGEGLYCNRTWDGWSCWDDTPAG VLAEQYCPDYFPDFDAAEKVTKYCGEDGDWYRHPESNISWSNYTMCNAFTPDKLQNAYIL YYLAIVGHSLSILTLLISLGIFMFLRYFNLLAPFNALLYPTRSISCQRVTLHKNMFLTYV LNSIIIIVHLVVIVPNGELVKRDPPICKVLHFFHQYMMSCNYFWMLCEGVYLHTLIVVSV FAEGQRLWWYHVLGWGFPLIPTTAHAITRAVLFNDNCWLSVDTNLLYIIHGPVMAALVVN FFFLLNILRVLVKKLKESQEAESHMYLKAVRATLILVPLLGVQFVVLPWRPSTPLLGKIY DYVVHSLIHFQGFFVAIIYCFCNHEVQGALKRQWNQYQAQRWAGRRSTRAANAAAATAAA AAALAETVEIPVYICHQEPREEPAGEEPVVEVEGVEVIAMEVLEQETSA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

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Datasheet & COA

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Target Background

Function(From Uniprot)

This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. The receptor can also couple to an additional signaling pathway via a pertussis toxin-sensitive g protein in isolated osteoclasts and in LLC-PK1 cells.

Gene References into Functions

Intracoronary intermedin 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin receptors and beta-adrenoreceptor-mediated nitric oxide release. PMID:19696365

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 2 family

Database Links

UNIGENE: Ssc.60684

KEGG: ssc:397638

STRING: 9823.ENSSSCP00000016247

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