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Recombinant Mouse Leukocyte surface antigen CD53 (Cd53)

Recombinant Mouse Leukocyte surface antigen CD53 (Cd53)

Code: CSB-CF736818MO

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Size:

20μg100μg

US$4126

Quantity:

Express system: in vitro E.coli expression system

Species: Mus musculus (Mouse)

Tag Info: N-terminal 10xHis-tagged

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Product Details
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Target Background

Product Details

Target Names

Cd53

Uniprot NO.

Q61451

Alternative Names

Cd53; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; CD antigen CD53

Species

Mus musculus (Mouse)

Source

in vitro E.coli expression system

Expression Region

2-219

Target Protein Sequence

GMSSLKLLKYVLFIFNLLFWVCGCCILGFGIYFLVQNTYGVLFRNLPFLTLGNILVIVGS IIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTIAILLFVYEQKLNTLVAEGLNDS IQHYHSDNSTMKAWDFIQTQLQCCGVNGSSDWTSGPPSSCPSGADVQGCYNKAKSWFHSN FLYIGIITICVCVIQVLGMSFALTLNCQIDKTSQALGL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells.

Gene References into Functions

Cd53-deficient B cells were defective in the phosphorylation of protein kinase C substrates. PMID:28487417
CD53 has a role in macrophage protection against LPS-induced oxidative stress and UVB irradiation PMID:15055538

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Subcellular Location

Cell membrane. Cell junction. Membrane; Multi-pass membrane protein. Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.

Protein Families

Tetraspanin (TM4SF) family

Database Links

UNIGENE: Mm.316861

KEGG: mmu:12508

STRING: 10090.ENSMUSP00000035781

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