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Recombinant Human Visual pigment-like receptor peropsin (RRH)

Recombinant Human Visual pigment-like receptor peropsin (RRH)

CSB-CF020517HU

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20μg100μg

US$5016

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Express system: in vitro E.coli expression system

Species: Homo sapiens (Human)

Tag Info: N-terminal 10xHis-tagged

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Target Background

Product Details

Target Names

RRH

Uniprot NO.

O14718

Species

Homo sapiens (Human)

Source

in vitro E.coli expression system

Expression Region

1-337

Target Protein Sequence

MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR KNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTK MSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKK FRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI

Protein Length

Full length protein

Tag Info

N-terminal 10xHis-tagged

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Description

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Target Background

Function

May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.

Gene References into Functions

Peropsin gene is not a common cause of retinitis pigmentosa or some related retinal degenerations, at least in the set of patients we analyzed. PMID:17167409

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family, Opsin subfamily

Tissue Specificity

Found only in the eye, where it is localized to the retinal pigment epithelium (RPE). In the RPE, it is localized to the microvilli that surround the photoreceptor outer segments.

Database Links

HGNC: 10450

UNIGENE: Hs.658310

KEGG: hsa:10692

STRING: 9606.ENSP00000314992

OMIM: 605224

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