Recombinant Human Somatostatin receptor type 3 (SSTR3)

1. the C-terminal phosphorylation motif of the human sst3 receptor that regulates its agonist-promoted phosphorylation, beta-arrestin recruitment, and internalization of this clinically relevant receptor, is reported. PMID:27101376
2. findings provide new insights in understanding the antiproliferative role of SSTR3 in breast tumor biology. PMID:26112183
3. In conclusions, in CNFAs, high expression of somatostatin receptors is much less common than that of D2R PMID:25536318
4. constitutive SSTR3 activity mediates transcriptional repression of GH. PMID:24606125
5. High SSTR3 expression is associated with gallbladder cancer. PMID:23991955
6. Determination of the expression of SSTR3 in an attempt to establish correlations and/or associations with clinical characteristics of patients with nonfunctioning pituitary adenomas. PMID:22419713
7. mRNA levels of SSTR2a, SSTR3 and SSTR5 in neuroendocrine lung cancer affected patients, were determined PMID:21503779
8. The cigarettes smoking and H. pylori infection are independent factors leading to decreasing of the SSTR3 mRNA level in gastric mucosa of patients with functional dyspepsia. PMID:20570798
9. There was a positive correlation between the percentage of tumor reduction by octreotide-lar and SSTR3 expression. PMID:19330452
10. expression of somatostatin (SS) and SS receptor (SSR) subtype 1 (sst1), sst2A, and sst3 in normal human thymic tissue PMID:12376335
11. localization and expression in human prostatic tissue and prostate cancer cell lines. PMID:12474541
12. Reduced SSTR3 expression is associated with gastric cancers PMID:15197339
13. Density of the SSTR3 receptor is decreased in gastric adenocarcinoma. H. pylori infection related reduction of the SSTR3 density in the antrum mucosa speaks for the need of eradication of these bacteria in the prevention of distal gastric cancer. PMID:17679363
14. Determine the influence of H. pylori infection and a family history of gastric cancer on the expression of SSTR3 in the gastric mucosa of non-cancer patients with dyspepsia. PMID:17683502
15. There was very little expression of SSTR3 in benign, premalignant, and cancerous laryngeal specimens; thus SSTR3 does not have an important role in laryngeal patholgy. PMID:18066572
16. Immunohistochemistry stufy of SSTR3 in prostate tissue from patients with bladder outlet obstruction showed that greatest proportion of basal cells showed a moderate intensity, strong immunoreactivity being observed only in 15.8% of cells. PMID:18936524
17. An interaction between the human somatostatin receptor 3 and the multiple PDZ protein MUPP1 was identified. PMID:19071123

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HGNC: 11332

UNIGENE: Hs.225995

KEGG: hsa:6753

STRING: 9606.ENSP00000330138

OMIM: 182453