Recombinant Guinea pig Integrin beta-6 (ITGB6)

Code: CSB-CF011890GU

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Size:

20μg100μg

US$6812

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Express system: in vitro E.coli expression system

Species: Cavia porcellus (Guinea pig)

Tag Info: N-terminal 10xHis-tagged

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Target Background

Product Details

Target Names

ITGB6

Uniprot NO.

P18563

Species

Cavia porcellus (Guinea pig)

Source

in vitro E.coli expression system

Expression Region

1-577

Target Protein Sequence

SASMDDDLNTIKELGSLLSKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEIANPCSSIP YICLPTFGFKHILPLTNDAERFNEIVKKQKISANIDNPEGGFDAIMQAAVCKEKIGWRND SLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVMEYPTIGQLIDKVVQ NNVLLIFAVTQEQVPLYENYAKLIPGATVGLLHKDSGNILQLIISAYEELRSEVELEVLG DTEGLNLSFSAVCNNGTLFPHQKKCLHMKVGETASFNVTVSIPNCERKSRHVIIKPVGLG DTLEILVSPECSCDCQKEVEVNSSKCHNGNGSYQCGVCACNPGHMGPHCECGEDTLSTDS CKETPDHPSCSGRGDCYCGQCICHLSPYGNIYGPYCQCDNFSCVRHKGLLCGDNGDCECG ECVCRSGWTGEYCNCTTSTDTCISEDGTLCSGRGDCVCGKCVCTNPGASGPTCERCPTCS DPCNSKRSCIECHLSADGQPGEECVDKCKLAGVTISKEADFSKDSSVSCSLQGENECLIT FLISTDNEGKTIIHNISEKDCPKPPNIPMIMLGVSLA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Troubleshooting and FAQs

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Target Background

Function(From Uniprot)

Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation.

Subcellular Location

Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.

Protein Families

Integrin beta chain family

Database Links

STRING: 10141.ENSCPOP00000011065

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