ICAM1; Intercellular adhesion molecule 1; ICAM-1; CD antigen CD54; Fragment
Species
Canis lupus familiaris (Dog) (Canis familiaris)
Source
in vitro E.coli expression system
Expression Region
25-528
Target Protein Sequence
QTSVDPAEAIILRGGSVQVNCSTSCNQTSIFGLETLLTKTEVTSGDNWVLFELTDVQEDSKLICFSNCHDETMAPIDLTVYWFPERVELAPLPRWQPVGENLTMTCQVAGGAPRTNLTVVLLRGEEELSRQPAVGEPAEVTFTVAVGREDHLANFSCRTDLDLRHRGLGLFQNSSAPRQLQTFVLPETPPRLATPPIVEVGTQWSVDCTMDGVFPASEAQVHLALAEERLHSTVLYKKDSLLATANVKANPEDEGTQQLWCEVTLGDENRRWQENVTFYSFPAPNLTLSEPEVSEWTTVTVECEAPAGVVVSLSGLPSGLAVPRAQFQLNASAADNRRSFSCSAALEVAGHMLQKNQTRELHVLYGPRLDQRDCPGNWTWEEGFHQTLKCQAWGNPVPELKCHRKGDDALLPIGDLRPVKREVAGTYLCQARSPRGEITREVVINVIYHQNNILIIILVTTIVILGTVSVAAYLYNRQRKIQKYKLQKAQEAAAMKLNTPATPP
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.