Home
Product
Protein
Transmembrane Proteins
Recombinant Danio rerio Sphingosine 1-phosphate receptor 2 (s1pr2)

Recombinant Danio rerio Sphingosine 1-phosphate receptor 2 (s1pr2)

Code: CSB-CF884843DIL

Rate （N/A）
Review （0）

Size:

20μg100μg

US$5263

Quantity:

Express system: in vitro E.coli expression system

Species: Danio rerio (Zebrafish) (Brachydanio rerio)

Tag Info: N-terminal 10xHis-tagged

Send an Inquiry

Start an on-line Chat

Online ordering is currently available for U.S. customers only. For orders outside the U.S., please kindly submit an inquiry or start a chat with us.

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Target Names

s1pr2

Uniprot NO.

Q9I8K8

Alternative Names

s1pr2; edg5; Sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P2; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Source

in vitro E.coli expression system

Expression Region

1-370

Target Protein Sequence

MTTCRLFAGFCQAVTMSKYSQYFNKTLIQVHYLTAKEMTAEELRDRIESKQSLSSLNILF VVICSIIILENLLVLIAVFRNKKFHSAMFFFIGNLAFSDLLAGSAYIANIFLSGPRTFHL TPVQWFIREGTAFIALSASVFSLLAIAIERYIAITKVKVYGSNKTCRMFLLIGACWVMSI LLGGLPIIGWNCINNLDDCSAVLPLNTRYYIRFVVTIFSIILLSIVILYVRIYLIVRTSH QEATNSPAYALLKTVTIVLGVFIICWLPAFTILLLDTSCKMKQCPILNNAGIFFSFATLN SALNPLIYTLRSKDMRKEFLRVLCCWGLLNCGRPPHRCMVPLKSSSSMEHCTNKHEHQSI PIMQDCTTCV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Troubleshooting and FAQs

Protein FAQs

Datasheet & COA

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P receptor is critical for cell migration and epithelial integrity during vertebrate embryogenesis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration.

Gene References into Functions

In embryos defective for S1pr2/Galpha13 signaling, endocardial precursors failed to migrate towards the midline, and the presumptive endocardium surrounded the bilaterally-located myocardial cells rather than being encompassed by them. PMID:27158029
beta-arrestin 2 and GRK2 colocalize with S1p2 in developing zebrafish embryos and depletion of GRK2 in the S1p2 R150H miles apart zebrafish partially rescued cardia bifida. PMID:25555130
S1pr2/Galpha13 signaling controls myocardial migration by regulating endoderm convergence. PMID:23318642
S1P(2) loss in a zebrafish mutant disrupted epithelial cell extrusion. PMID:21555463
mil encodes Edg5, a sphingosine-1-phosphate receptor. PMID:18701549