Recombinant Chicken Tyrosinase (TYR)

Code: CSB-CF025394CH
Size:
20μg
20μg100μg
US$6318
Quantity:
Express system: in vitro E.coli expression system
Species: Gallus gallus (Chicken)
Tag Info: N-terminal 10xHis-tagged
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Product Details

Target Names
TYR
Uniprot NO.
Species
Gallus gallus (Chicken)
Source
in vitro E.coli expression system
Expression Region
19-529
Target Protein Sequence
QFPRVCANTQSLLRKECCPPWDGDGTPCGERSNRGTCQRILLSQAPLGPQFPFSGVDDREDWPSVFYNRTCRCRGNFMGFNCGECKFGFSGQNCTERRLRTRRNIFQLTISEKDKFLAYLNLAKNIPSKDYVIATGTYAQMNNGSNPMFRNINVYDLFVWMHYYASRDTLLGGSNVWRDIDFAHEAPGFLPWHRAFLLLWEREIQKITGDENFTIPYWDWRDAEDCVICTDEYMGGQHPTNPNLLSPASFFSSWQVICTQSEEYNSQQALCNATSEGPILRNPGNNDKSRTPRLPSSSEVEFCLTLTQYESGSMDKMANYSFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFERWLRRHRPMLEVYPAANAPIGHNRENYMVPFIPLYRNGEFFISSRELGYDYEYLQEPALGSFQDFLIPYLKQAHQIWPWLVGAAVIGGIITAVLSGLILACRKKRKGTSPEIQPLLTESEDYNNVSYQSHF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Troubleshooting and FAQs
Datasheet & COA
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Gene References into Functions
  1. Individuals with genotypes AA and AT had greater TYR expression than those with genotype TT. A luciferase assay of the promoter activity revealed that genotype AA had greater activity than genotype TT. PMID:29050424
  2. The co-segregation of plumage coloration and sequence polymorphism in TYR and MC1R genes were investigated using an intercross between black and white plumage color types of the Dongxiang blue-shelled chicken. PMID:20460655
  3. This study provided original information for elucidating the possible roles of exon-1 of TYR gene and 5' flanking region in chickens with different flesh color chicken. PMID:19437131
  4. Mutated proteins showed the insertion of a complete avian retroviral sequence of the Avian Leukosis Virus (ALV) family. PMID:16457736
  5. An avian retroviral sequence insertion in the tyrosinase gene was the cause of recessive white phenotype in chickens. PMID:17878441

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Subcellular Location
Melanosome membrane; Single-pass type I membrane protein. Melanosome.
Protein Families
Tyrosinase family
Database Links

UNIGENE: Gga.928

KEGG: gga:373971

STRING: 9031.ENSGALP00000027812

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