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Recombinant Chicken Tumor necrosis factor receptor superfamily member 16 (NGFR)

Recombinant Chicken Tumor necrosis factor receptor superfamily member 16 (NGFR)

Code: CSB-CF015780CH

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Size:

20μg100μg

US$5465

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Express system: in vitro E.coli expression system

Species: Gallus gallus (Chicken)

Tag Info: N-terminal 10xHis-tagged

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Product Details
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Target Background

Product Details

Target Names

NGFR

Uniprot NO.

P18519

Alternative Names

NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD

Species

Gallus gallus (Chicken)

Source

in vitro E.coli expression system

Expression Region

20-416

Target Protein Sequence

SKEKCLTKMYTTSGECCKACNLGEGVVQPCGVNQTVCEPCLDSVTYSDTVSATEPCKPCTQCVGLHSMSAPCVESDDAVCRCAYGYFQDELSGSCKECSICEVGFGLMFPCRDSQDTVCEECPEGTFSDEANFVDPCLPCTICEENEVMVKECTATSDAECRDLHPRWTTHTPSLAGSDSPEPITRDPFNTEGMATTLADIVTTVMGSSQPVVSRGTADNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANNRPVNQTPSPEGEKLHSDSGISVDSQSLHDQQPPNQSTQGPAPKGDGSLYASLPPSKQEEVEKLLSSSAEETWRQLAGELGYKEDLIDCFTREESPARALLADWSAKETATLDALLVALRKIQRGDIAESLYSESTATSPV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Necessary for the circadian oscillation of clock genes in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, dendritic spine.

Tissue Specificity

Detected in embryonic dorsal root ganglion and retina.

Database Links

UNIGENE: Gga.39799

STRING: 9031.ENSGALP00000020402

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