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Recombinant Bovine Follicle-stimulating hormone receptor (FSHR)

Recombinant Bovine Follicle-stimulating hormone receptor (FSHR)

Code: CSB-CF009021BO

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Size:

20μg100μg

US$7568

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Express system: in vitro E.coli expression system

Species: Bos taurus (Bovine)

Tag Info: N-terminal 10xHis-tagged

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Target Background

Product Details

Target Names

FSHR

Uniprot NO.

P35376

Species

Bos taurus (Bovine)

Source

in vitro E.coli expression system

Expression Region

18-695

Target Protein Sequence

CHHRLCHCSNGVFLCQESKVTEIPSDLPRDAVELRFVLTKLRVIPKGAFSGFGDLEKIEI SQNDVLEVIEANVFSNLPKLHEIRIEKANNLLYIDPDAFQNLPNLRYLLISNTGIKHLPA VHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMTVWLSKNGIQEIHNCAFNGTQLDE LNLSDNSNLEELPNDVFQGASGPVILDISRTRIRSLPSYGLENLKKLRAKSTYRLKKLPS LEKFVTLVEASLTYPSHCCAFANWRRQTSDLHPICNKSILRQEVDDMTQARGQRVSLAED DEPSYAKGFDVMYSEFDYDLCNEVVDVTCSPEPDAFNPCEDIMGDDILRVLIWFISILAI TGNILVLVILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDVHTKTEYHNYAIDWQ TGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLECKVQLRHAASIMLVGWIFA FAVALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICGCYTHIYLTVR NPNITSSSSDTKIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPI NSCANPFLYAIFTKNFRRDFFILLSKFGCYEVQAQTYRSETSSTAHNFHPRNGHCPPAPR VTNGSNYTLIPLRHLAKN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

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Target Background

Function(From Uniprot)

G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.

Gene References into Functions

INVESTIGATION OF STAT5A, FSHR AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS PMID:26845856
The expression of FSHR mRNA in granulosa cells was highest in small antral follicles, then decreased significantly as follicles increased in size, and was lowest in cysts. PMID:25454493
transfer. We conclude that variation at these loci of the FSHR gene has no significant effect on pregnancy rates in Luxi cattle. PMID:24668630
Specific alleles of the bovine FSHR gene are associated with variations in embryo yield and in the number of unfertilised oocytes. PMID:22670622
This study evaluated the relationships among aromatase, IGF-1, IGF2R, and follicle stimulating hormone (FSH) receptor levels expressed in ovarian follicles of cattle selected for twin pregnancies. PMID:22266997
granulosa cell clustering is accompanied by marked increases in FSHr, IGF-1r, and p450 arom expression, and precedes induction and subsequent peak E2 production PMID:12782408
Dominant follicles experience a reduction in FSH dependence (diminished expression of FSHR), but acquire increased LH dependence (enhanced expression of LHCGR) as they grow during the low FSH milieu of follicular waves. PMID:16481595
FSHR is specifically regulated through androgen receptor in granulosa cells PMID:16641147
Heterozygous heifers showed a higher pregnancy rate (67 and 66% for LHR and FSHR genes, respectively), but no significant effects were observed for the genes studied ( PMID:18393228