Recombinant Bovine ATP-binding cassette sub-family G member 2 (ABCG2)

1. ABCG2 single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle. PMID:27468856
2. These findings point to a significant role of the ABCG2 Y581S polymorphism in the milk disposition of enterolactone and the endogenous molecules riboflavin and uric acid, which could affect both milk quality and functionality. PMID:26510964
3. The results suggest that a mutation of SCD1, but not LEPR or ABCG2, might be useful as a DNA marker to decrease reproductive problems and improve production traits in Iranian Holstein dairy cows. PMID:25130486
4. P-gp, Bcrp and Mrp1 are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport. PMID:24934296
5. This study has, for the first time, confirmed the expression of ABCG2 in epithelial cells of the bovine rumen. PMID:24747985
6. These results contribute to the role of ABCG2 in cytoprotection and disposition in important tissue barriers and may have important implications for veterinary pharmacotherapy of dairy animals. PMID:23473424
7. Generated cell culture model allows rapid and high-throughput screening of potential ruminant ABCG2 substrate, increasing the understanding of carrier-associated secretion of xenobiotics into milk. PMID:23192864
8. Bovine ABCG2 Tyr581Ser single-nucleotide polymorphism increases milk secretion of the veterinary antibiotic danofloxacin. PMID:23230133
9. ABCG2 plays a role in mammary epithelial cell proliferation, and functional polymorphisms in this gene may influence the cellular compartment of the mammary gland and potentially milk production. PMID:22870877
10. plays a role in epididymal sperm maturation, but not after ejaculation PMID:22441796
11. The effect of the Y581S polymorphism of ABCG2 on transcellular transport of veterinary drugs was studied because this could alter substrate pharmacokinetics and milk residues. PMID:21821808
12. Data suggest that the BB genotype of bovine ABCG2 is a molecular marker for superior milk performance. PMID:20140710
13. The recent progress in mapping quantitative trait nucleotides (QTNs) are reviewed, including the ABCG2 gene mutation that underlies a QTL for fat and protein content and the ovine MSTN gene mutation that causes muscular hypertrophy in Texel sheep. PMID:20720303
14. associated with increased fat yield, fat and protein percent as well as decrease in milk yield; also in Bos indicus and Bubalus bubalis PMID:17087837
15. The allele frequencies of ABCG2(A) and ABCG2(C) were determined in 32 Bos taurus and 3 Bos indicus breeds. The detection of ABCG2(C) only in Bos taurus breeds may indicate that ABCG2(A) is the ancestral allele. PMID:17106124
16. The C allele of ABCG2_49 is found in a marker haplotype that has an extremely negative effect on fat and protein percentages and positive effect on milk yield PMID:17584938

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UNIGENE: Bt.51973

STRING: 9913.ENSBTAP00000051068