CAMK2A/CAMK2B/CAMK2G/CAMK2D Recombinant Monoclonal Antibody

Code: CSB-RA922077A0HU

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Size:

50μl100μl

US$210

Quantity:

Species Reactivity: Human

Application: ELISA, IHC

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Target Background

Product Details

Uniprot NO.

Q9UQM7 Q13554 Q13555 Q13557

Target Names

CAMK2A/CAMK2B/CAMK2G/CAMK2D

Alternative Names

Calcium/calmodulin dependent protein kinase II alpha antibody; Calcium/calmodulin dependent protein kinase II beta antibody; Calcium/calmodulin dependent protein kinase II delta antibody; Calcium/calmodulin dependent protein kinase II gamma antibody; Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody; CaM kinase II alpha antibody; CaM kinase II antibody; CaM kinase II beta antibody; CaM kinase II delta antibody; CaM kinase II gamma antibody; CaM kinase II subunit alpha antibody; CaMK-II subunit alpha antibody; CAMK2 antibody; Camk2a antibody; CAMK2B antibody; CAMK2D antibody; CAMK2G antibody; CAMKA antibody; KCC2A_HUMAN antibody; Calcium/calmodulin dependent protein kinase (CaM kinase) II beta antibody; Calcium/calmodulin dependent protein kinase II beta antibody; Calcium/calmodulin dependent protein kinase IIB antibody; Calcium/calmodulin dependent protein kinase type II beta chain antibody; calcium/calmodulin-dependent protein kinase II beta antibody; Calcium/calmodulin-dependent protein kinase type II subunit beta antibody; CAM 2 antibody; CaM kinase II beta chain antibody; CaM kinase II beta subunit antibody; CaM kinase II subunit beta antibody; CaM-kinase II beta chain antibody; CAM2 antibody; CAMK 2 antibody; CAMK 2B antibody; CaMK II beta subunit antibody; CaMK II subunit beta antibody; CaMK-II subunit beta antibody; CAMK2 antibody; CaMK2 beta antibody; Camk2b antibody; CAMKB antibody; CaMKII beta subunit antibody; CaMKIIB antibody; KCC2B_HUMAN antibody; MGC29528 antibody; Proline rich calmodulin dependent protein kinase antibody; proline rich calmodulin-dependent protein kinase antibody; CAMK2G antibody; CAMK antibody; CAMK-II antibody; CAMKGCalcium/calmodulin-dependent protein kinase type II subunit gamma antibody; CaM kinase II subunit gamma antibody; CaMK-II subunit gamma antibody; EC 2.7.11.17 antibody; Calcium / calmodulin dependent protein kinase 2 delta antibody; Calcium / calmodulin dependent protein kinase II delta antibody; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta antibody; calcium/calmodulin-dependent protein kinase type II delta chain antibody; Calcium/calmodulin-dependent protein kinase type II subunit delta antibody; CAM kinase 2 delta antibody; CAM kinase II delta antibody; CaM kinase II delta subunit antibody; CaM kinase II subunit delta antibody; CaM-kinase II delta chain antibody; CAMK 2d antibody; CaMK-II delta subunit antibody; CaMK-II subunit delta antibody; CAMK2D antibody; CAMKD antibody; CAMKI antibody; KCC2D_HUMAN antibody; RATCAMKI antibody

Species Reactivity

Human

Immunogen

A synthesized peptide from human CAMK2A/CAMK2B/CAMK2G/CAMK2D protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

Rabbit IgG

Clone No.

5A1

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:200

Protocols

ELISA Protocol Immunohistochemistry (IHC) Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

Antibody FAQs

Images

IHC image of CSB-RA922077A0HU diluted at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

Description

Calcium/calmodulin-dependent protein kinase II represents one of the most abundant and functionally critical kinases in the central nervous system, serving as a master regulator of synaptic plasticity, learning, and memory formation. The CAMK2 family comprises four closely related isoforms—alpha, beta, gamma, and delta—each contributing to calcium-mediated signal transduction across diverse cellular contexts. Beyond neuronal function, these kinases participate in cardiac contractility, cell cycle regulation, and cytoskeletal dynamics, making them essential targets for researchers investigating neurodegenerative diseases, cardiac pathophysiology, and cancer biology.

This recombinant monoclonal antibody, clone 5A1, offers the reproducibility and consistency that demanding experimental workflows require. Generated against a synthesized peptide encompassing conserved regions across human CAMK2A, CAMK2B, CAMK2G, and CAMK2D, this antibody enables simultaneous detection of multiple family members, providing a comprehensive view of CAMK2 expression patterns. The recombinant production platform ensures sequence-defined specificity and eliminates the lot-to-lot variability that can compromise longitudinal studies.

Validation in immunohistochemistry demonstrates reliable performance in paraffin-embedded human glioma tissue, where the antibody successfully detected CAMK2 expression at 1:100 dilution using standard citrate-based antigen retrieval. This validation in brain tumor tissue is particularly relevant given the established roles of CAMK2 isoforms in glioma progression and neural tissue biology.

Supplied in a glycerol-containing buffer optimized for long-term stability, this antibody supports researchers investigating synaptic signaling mechanisms, neurological disorders, and the emerging connections between calcium signaling and tumor biology.