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Recombinant Xiphophorus maculatus Cellular tumor antigen p53 (tp53)

Recombinant Xiphophorus maculatus Cellular tumor antigen p53 (tp53)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

tp53

Purity

>85% (SDS-PAGE)

Target Names

tp53

Uniprot NO.

Q92143

Alternative Names

tp53; p53; Cellular tumor antigen p53; Tumor suppressor p53

Species

Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)

Source

Yeast

Expression Region

1-342

Target Protein Sequence

MEEADLTLPL SQDTFHDLWN NVFLSTENES LPPPEGLLSQ NMDFWEDPET MQETKNVPTA PTVPAISNYA GEHGFNLEFN DSGTAKSVTS TYSVKLGKLF CQLAKTTPIG VLVKEEPPQG AVIRATAVYK KTEHVGEVVK RCPHHQSEDL SDNKSHLIRV EGSQLAQYFE DPNTRRHSVT VPYERPQLGS EMTTILLSFM CNSSCMGGMN RRPILTILTL ETTEGEVLGR RCFEVRVCAC PGRDRKTEEG NLEKSGTKQT KKRKSAPAPD TSTAKKSKSA SSGEDEDKEI YTLSIRGRNR YLWFKSLNDG LELMDKTGPK IKQEIPAPSS GKRLLKGGSD SD
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

P53 family

Database Links

KEGG: xma:102219062

STRING: 8083.ENSXMAP00000015753

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