Recombinant Xenopus tropicalis Beclin-1 (becn1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

becn1

Purity

>85% (SDS-PAGE)

Target Names

becn1

Uniprot NO.

Q4A1L3

Alternative Names

becn1Beclin-1

Species

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Source

Yeast

Expression Region

1-445

Target Protein Sequence

METSKSSTMQ VSFVCQRCSQ PLKLDTSFKI LDKVTMQELT APLVTTAAVK PGDIQEVDSN IEETFAENRT DGVSRRLIPP ARMMSTESAT SFTLIGEASD GGTMENLSRR LKVTGDLFDI MSGQTDVDHP LCEECTDTLL DQLDTQLNIT ENECQNYKRC LEILERMNED DKEKLEAKLK ELAEDEDRLI QELEEVERNR ELVAKDIEKV REEAERLEQE EARYQKEYSE FKRQQLELDD DLKSVENQMR YAQIQLDKLK KTNVFNATFH IWHSGQFGTI NNFRLGRLPS VPVEWNEINA AWGQTVLLLH ALANKMGLQF QRYRLMPFGN HSYLESLTDK SKELPLYCSG GLRFFWDNKF DHAMVAFLDC VQQFKEEVEK GDTGFCLPYR MDVEKGKIED TGGSGGSYSI KTQFNSEEQW TKALKFMLTN LKWGLAWVSS QFYNK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis including endosome formation in neuronal cells.

Subcellular Location

Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome.

Protein Families

Beclin family

Database Links

UNIGENE: Str.27054

KEGG: xtr:619357

STRING: 8364.ENSXETP00000027611

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