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Recombinant Xenopus laevis Ubiquitin carboxyl-terminal hydrolase 16 (usp16), partial

Recombinant Xenopus laevis Ubiquitin carboxyl-terminal hydrolase 16 (usp16), partial

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MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

usp16

Purity

>85% (SDS-PAGE)

Target Names

usp16

Uniprot NO.

Q6PAW2

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-901

Target Protein Sequence

MVKKRGTNLP AQDFLDAEPV CKHLRKALDD GSVKRALVNV EWTMCQDCQA DNKEKNNSED ESAEDPSVWL CLKCGHRGCG RNSVAQHALN HYNTPRSEPH CLVLNVDMWS AWCYLCDNEV PYNRTSRLGQ LVDYLQRKAK AKNKNSNSVV SNEEVKTEIV TENEVKKIQY QDEKPDVQAK QEKASSTQKI STEPTVKGLS NLGNTCFFNA VMQNLSQTPA LSELLNEVKT FRKPVTVLLP DSSSPKILEV NLEQQPGPLT LAMWQFLTEM HETKKGVVTP KELFSQVCKK AIRFKGYQQQ DSQELLRYLL DGMRGEEIQR VTLAMSKSLQ STLDEEEIKK IVKDYEKRRT IPNFVDCLFG GELTSTIMCE ECHTVSLVHE PFLDLSLPVL DDLIVKKNSK STPPARERKE EEEEEENDDD RYVKERDEVS PGASKHLQKK AKKAAKKQAK NQRRQQKWQG KTVLFTDLAK QECSEDEEEV SQTKTNTRPD NETPTADGLN TMETDLSTLE NGNEESADGL NTMETDLSTL ENGNEEMAGG FKTMEMDLST LENGSETIKS AVEGITEHTD LDSSVHNNVG SVETNALVGN MENNNNIEVN KTPERTAGSG GDSMEAMAAV ENGNADAVNV DDTEAVNGLI DSANMDHELT NSLNRLQLSS DLEPTQVEIE ILPDKEQPHT QVYEVVNEDP KTAFSTLSNR KDLPIDEFSV LSCLYQFTHK ETLTGNNKLL CNVCTRKQAS RLNNSNKGEK KFVYTNAKKQ MLVSNPSPIL TLHLKRFQQN GFNLRKINRH IKFPEVLDLA PFCTAKCKNV PEGESRLLYS LYGVIEHSGS MRSGHYTAFV KLRHPNQQLC KMLFTGVIPE VSGSEPGQGS WYHISDSHVQ AVSLSRVLSS QAYLLFYERM L
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

Subcellular Location

Nucleus.

Protein Families

Peptidase C19 family, USP16 subfamily

Database Links

UNIGENE: Xl.32808

KEGG: xla:398823

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