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Recombinant Xenopus laevis Transcription factor GATA-4 (gata4)

Recombinant Xenopus laevis Transcription factor GATA-4 (gata4)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

gata4

Purity

>85% (SDS-PAGE)

Target Names

gata4

Uniprot NO.

Q91677

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-392

Target Protein Sequence

MYQSIAMATN HGPSGYEGTG SFMHSATAAT SPVYVPTTRV SSMIHSLPYL QTSGSSQQGS PVSGHNMWAQ AGVESSAYNP GTSHPPVSPR FTFSSSPPIT APSSREVSYS SPLGISANGR EQYSRGLGAT YASPYPAYMS PDMGAAWTAS PFDSSMLHNL QNRAVTSRHP NIEFFDDFSE GRECVNCGAM STPLWRRDGT GHYLCNACGL YHKMNGINRP LIKPQRRLSA SRRVGLSCAN CHTTTTTLWR RNAEGEPVCN ACGLYMKLHG VPRPLAMKKE GIQTRKRKPK NLSKSKTLTG QSGSDSLTPS TSSTNSMGEE MRPIKIEPGL SPPYDHSNSI SQASALSTIT SHGSSYYPMP SLKLSPQNHH STFNPSPQAN SKHDSWNNLV LA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3'. Associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Activates the expression of cardiac MHC-alpha in vivo.

Gene References into Functions

The data demonstrate that KLF13 is an important component of the transcription network required for heart development and suggest that KLF13 is a GATA-4 modifier PMID:17053787

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Subcellular Location

Nucleus.

Tissue Specificity

Expressed at high levels in heart, small intestine, stomach, ovary, and liver. Found at much lower levels in lung, spleen, pancreas and skin.

Database Links

UNIGENE: Xl.1061

KEGG: xla:399302

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