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Recombinant Xenopus laevis Suppressor of hairless protein homolog (rbpj), partial

Recombinant Xenopus laevis Suppressor of hairless protein homolog (rbpj), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

rbpj

Purity

>85% (SDS-PAGE)

Target Names

rbpj

Uniprot NO.

Q91880

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-501

Target Protein Sequence

MQPGIPKYTP SAIQLAPVVT GKFGERPQPK RLTREAMRNY LKERGDQTVL ILHAKVAQKS YGNEKRFFCP PPCVYLMGSG WKKKKEQMER DGCSEQESQP CAFIGIGNSE QEMQQLNLEG KNYCTAKTLY ISDSDKRKHF MLSVKMFYGN SDDIGVFLSK RIKVISKPSK KKQSLKNADL CIASGTKVAL FNRLRSQTVS TRYLHVEGGN FHASSQQWGA FYIHLLDDEE SEGEEFTVRD GYIHYGQTVK LVCSVTGMAL PRLIIRKVDK QTALLDADDP VSQLHKCAFY LKDTERMYLC LSQERIIQFQ ATPCPKEPNK EMINDGASWT IISTDKAEYT FYEGMGPINA PVTPVPVVES LQLNGGGDVA MLELTGQNFT PNLRVWFGDV EAETMYRCAE SMLCVVPDIS AFREGWRWVR QPVQVPVTLV RNDGVIYSTS LTFTYTPEPG PRPHCSAAGA ILRANSSLLA SNEPNTNSEG SYTNISTNSA NVTSSTAAVV S
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Required for the transcriptional activation of ESR1, suggesting that it is required during primary neurogenesis in embryos. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen).

Gene References into Functions

The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52) as a novel rbpj/CBF-1-interacting protein. PMID:21102556
The results suggest that a cell-to-cell interaction via the Notch/Su(H) pathway has a significant role in the PGC migration by regulating cell motility. PMID:20151992

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Subcellular Location

Nucleus. Cytoplasm.

Protein Families

Su(H) family

Database Links

UNIGENE: Xl.12006

KEGG: xla:399453

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