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Recombinant Xenopus laevis Splicing factor 3B subunit 1 (sf3b1), partial

Recombinant Xenopus laevis Splicing factor 3B subunit 1 (sf3b1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

sf3b1

Uniprot NO.

O57683

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-1307

Target Protein Sequence

MAKVAKTHED IEAQIREIQG KKAALDEEEG VGLDSTGYFD QEIYGGSDSR FTGYVTSIAA NEQEDDDDDV SSATFEQKKP GYHAPVALLN DIPQSTEQYD PFAEHRPQKI ANREDEYKQQ RRKMIISPER LDPFADGGKT PDPKLNARTF KDVMQEQYLT KEEREIRQQI AEKAKSGDLK VVNGSSASSA AQPPSKRKRR WDQTGDQTPG STPKKLSSWD QAEVTPGHTP SSLRWDETPG RAKGNETPGA TPGSKIWDPT PSHTPAGVAT PGRGDTPGHV TPGHSGATSS ARKNRWDETP KTERDTPGHG SGWAETPRTD RGGDSIGETP TPGASKRKSR WDETPASQMG GSTPVLTPGK TPIGTPAMNM ATPTPGHIMS MTPEQLQAWR WEREIDERNR PLSDEELDAM FPEGYKVLPP PAGYVPIRTP ARKLTATPTP LGGLTGFHMP TEDRSMKSVS DQPSGNLPFL KPDDIQYFDK LLVDVDESTL SPEEQKERKI MKLLLKIKNG TPPMRKAALR QITDKAREFG AGPLFNQILP LLMSPTLEDQ ERHLLVKVID RILYKLDDLV RPYVHKILVV IEPLLIDEDY YARVEGREII SNLAKAAGLA TMISTMRPDI DNMDEYVRNT TARAFAVVAS ALGIPSLLPF LKAVCKSKKS WQARHTGIKI VQQIAILMGC AILPHLRSLV EIIEHGLVDE QQKVRTISAL AIAALAEAAT PYGIESFDSV LKPLWKGIRQ HRGKGLAAFL KAIGYLIPLM DAEYANYYTR EVMLILIREF QSPDEEMKKI VLKVVKQCCG TDGVEANYIK TEILPPFFKH FWQHRMALDR RNYRQLVDTT VELANKVGAA EIISRIVDDL KDEAEQYRKM VMETIEKIMG NLGAADIDHK LEEQLIDGIL YAFQEQTTED SVMLNGFGTV VNALGKRVKP YLPQICGTVL WRLNNKSAKV RQQAADLISR TAVVMKTCQE EKLMGHLGVV LYEYLGEEYP EVLGSILGAL KAIVNVIGMH KMTPPIKDLL PRLTPILKNR HEKVQENCID LVGRIADRGA EYVSAREWMR ICFELLELLK AHKKAIRRAT VNTFGYIAKA IGPHDVLATL LNNLKVQERQ NRVCTTVAIA IVAETCSPFT VLPALMNEYR VPELNVQNGV LKSLSFLFEY IGEMGKDYIY AVTPLLEDAL MDRDLVHRQT ASAVVQHMSL GVYGFGCEDS LNHLLNYVWP NVFETSPHVI QAVMGALEGL RVAIGPCRMV QYCLQGLFHP ARKVRDVYWK IYNSIYIGSQ DALIAHYPRI YNDEKNTYIR YELDYTL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Subcellular Location

Nucleus.

Protein Families

SF3B1 family

Database Links

UNIGENE: Xl.2599

KEGG: xla:399336

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