Home
Product
Protein
Recombinant Proteins
Recombinant Xenopus laevis Serine/threonine-protein kinase TBK1 (tbk1), partial

Recombinant Xenopus laevis Serine/threonine-protein kinase TBK1 (tbk1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

tbk1

Purity

>85% (SDS-PAGE)

Target Names

tbk1

Uniprot NO.

Q6DFJ6

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-725

Target Protein Sequence

MQSTANYLWM LSDILGQGAT ANVYRGRNKK TGDLYAVKVF NSLSFQRPAD VQMREFEVLK KLNHKNIVKL FAIEEEMSSR HKVLVMEFCP CASLYSVLEE PTNSYGLPES EFLIVSRDVV AGMNHLRENG IIHRDIKPGN IMREIGEDGK SVYKLTDFGA ARELEDDEQF VSLYGTEEYL HPDMYERAVL RKEHQKKYSA TVDLWSIGVT FYHAATGSLP FRPFEGPRRN KEVMYKIIAG KPSGAISGVQ RAENGPIEWS GELPATCNLS MGLQTLFTPV LANILEADQE KCWGFEQFFA VTNDIFNRIV VHVFSLQQMT PHKIYINTYD KVPDFHDLVY KQTKIPGQNQ ELLFEGRRLV LEQGRLAQHF PITTDENPIF VLTREMVSVI GLRFDEIVIP KPISHYDLDV DANMAKAVTG VACYYCRIAA SLLLVLDLMR KGIRWLSELM KEEYNENVHR NTEVSLKLNF CNRTTEKDLK IYEQLMQTSV ESEVYAIHAK LLNLSSTQEG LKSSLQEVKN KLTPGGTLMD SWINTEGIHA ADRNVEKLQV LLSLITEIYC QFKKDKAQRR LSYNEEQIHK FDKQKLCLHA AKAYSLFKDE CVGKYEVFRS KTLEWMRKMI HVRKQLFSIK SKCFDIEEEA SKCQHYINQY QEKMSPKMFA APSGMKSAVN PIYSSPNTLV EMTLGMRKLK EDMEGVVKEL EENNHILERF GALTIDGDFR NVDCI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with traf3 and tank and phosphorylates interferon regulatory factors (IRFs) irf3 and irf7 as well as ddx3x. This activity allows subsequent homodimerization and nuclear translocation of the IRFs leading to transcriptional activation of pro-inflammatory and antiviral genes including ifna and ifnb. In order to establish such an antiviral state, TBK1 form several different complexes whose composition depends on the type of cell and cellular stimuli.

Subcellular Location

Cytoplasm.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily

Database Links

UNIGENE: Xl.25092

KEGG: xla:446351

Promotions