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Recombinant Xenopus laevis SHC-transforming protein 1 (shc1)

Recombinant Xenopus laevis SHC-transforming protein 1 (shc1)

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MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

shc1

Purity

>85% (SDS-PAGE)

Target Names

shc1

Uniprot NO.

Q8AY68

Alternative Names

shc1; SHC-transforming protein 1; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1; p60Shc

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-465

Target Protein Sequence

MNKLSCGRKS RVEGGQLAGD EWTRHGSFVN KPTRGWLHPD DKVMGPGVPY LVRYMGCVEV LQSMRALDFN TRTQVTREAI SLVCDAVPGA KGAMRRRKTC GRSLNSILGK SNLKFAGMPI TLTVSTSSLN LMASDCKQII ANHHMQSISF ASGGDPDTAE YVAYVAKDPV NQRACHILEC PEGLAQDVIS TIGQAFELRF KQYLKNPPKL VTPHDRMAGF DGSAWDEEEE ELPDHAYYND FPGKEPPIGG VVDMRLRDGA APAVLRQSPN HMGATLPVGQ VSGAEQDSRK MQPTLQGRER FPVPCSRPPN RPDLFDDPSY VNVQNLEKSR QPLRAANGQR DIFDMKPFDD ALPSAQAIVS MEDQLKREPW YQGKMSRKEA ERLLKVNGDF LVRESTTTPG QYVLTGLQCG QPKHLLLVDP EGVVRTKDHR FESVSHLISY HMDNHLPIIS AGSELCLQQP VERRQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Implicated in ras-dependent oocyte maturation induced by insulin/IGF-1.

Gene References into Functions

ShcA is required for Wnt-5a/Ror2 mediated upregulation of xPAPC, which demonstrates the functional relevance of this interaction. PMID:20732301

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Subcellular Location

Cytoplasm.

Tissue Specificity

Highly expressed in oocytes and embryo. Also expressed in liver. Detected in ovary, testis and heart and to a lesser extent in liver (at protein level).

Database Links

UNIGENE: Xl.3210

KEGG: xla:399198

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