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Recombinant Xenopus laevis Runt-related transcription factor 1 (runx1)

Recombinant Xenopus laevis Runt-related transcription factor 1 (runx1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

runx1

Purity

>85% (SDS-PAGE)

Target Names

runx1

Uniprot NO.

Q6PF39

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-462

Target Protein Sequence

MRIPVDTSTS RRFTPPSTTL SPGKMSEPIP LNIADSSAAL VGKLRSTDRN MVEVLSDHPG ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGEVPDG TLVTVMAGND ENYSAELRNA TAAMKSQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR QKLDEQTKPG NLSFSERLSE LEHFRRTAMR VSPHHPNPMP NPRATLNHSA AFNPQPQGQI QVADTRQVQA SPPWSYDQSY QYLGSIATQS VHPATPISPG RASSMTSLSA ELSSRLSGAS DLTAFSDPRV GIDRQFSTLP SISDPRMHYP GAFTYTPTPV TSGIGIGMSA MTSATRYHTY LPPPYPGSSQ AQSNPFQTSS PSYHLYYGTS AGSYHQFSMM SGGERSPPRI LPPCTNASTG STLLNPNLPN QSDVVEAEGS HSNSPTNMGS TPRLEEAVWR PY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in primitive hematopoiesis in the embryo.

Gene References into Functions

Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus. PMID:22173066
ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL). PMID:20658612
reveal a shift in Runx2 function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage PMID:17474117

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Subcellular Location

Nucleus.

Tissue Specificity

Shows a complex and dynamic expression pattern. In stage 14-24 embryos, expressed in a subset of neuroblasts in the lateral stripe of the neural plate. In late neurula stages, expression begins in the olfactory placodes. Also expressed in structures that

Database Links

UNIGENE: Xl.2874

KEGG: xla:379657

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