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Recombinant Xenopus laevis Protein snail homolog Sna (snai1)

Recombinant Xenopus laevis Protein snail homolog Sna (snai1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

snai1

Uniprot NO.

P19382

Alternative Names

snai1; sna; Protein snail homolog Sna; Protein Xsnail; Protein xSna

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-259

Target Protein Sequence

MPRSFLVKKH FSASKKPNYS ELESQTVYIS PFIYDKFPVI PQPEILSTGA YYTPLVWDTG LLTTFFTSES DYKKSPISPS SSDDSSKPLD LTSFSSEDEG GKTSDPPSPA SSATEAEKFQ CNLCSKSYST FAGLSKHKQL HCDSQTRKSF SCKYCEKEYV SLGALKMHIR SHTLPCVCKI CGKAFSRPWL LQGHIRTHTG EKPFSCTHCN RAFADRSNLR AHLQTHSDVK KYQCKSCSRT FSRMSLLHKH EETGCTVAH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Transcriptional repressor. Acts upstream of snai2/slug, zic5 and other neural crest markers in the specification of the neural crest and neural crest migration. Involved in embryonic mesoderm formation.

Gene References into Functions

The transcription factor Snail1 is essential for tissue separation, enabling paraxial protocadherin (PAPC) to promote tissue separation through novel functions. PMID:25778923
the same E3 ubiquitin ligase known to regulate Snail family proteins, Partner of paired (Ppa), also controlled Twist stability and did so in a manner dependent on the Twist WR-rich domain PMID:21727196

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Subcellular Location

Nucleus.

Protein Families

Snail C2H2-type zinc-finger protein family

Tissue Specificity

Maternal expression is nearly completely restricted to the vegetal hemisphere. Zygotic expression begins in the dorsal marginal zone just before gastrulation (stage 9), and is almost completely absent in the animal hemisphere. At mid-gastrula (stage 11-11

Database Links

UNIGENE: Xl.13309

KEGG: xla:379615

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