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Recombinant Xenopus laevis Pro-neuregulin-1, membrane-bound isoform (nrg1), partial

Recombinant Xenopus laevis Pro-neuregulin-1, membrane-bound isoform (nrg1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

nrg1

Uniprot NO.

O93383

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Direct ligand for the ERBB tyrosine kinase receptors. Induces expression of acetylcholine receptor in synaptic nuclei.

Gene References into Functions

Cloning of a novel isoform of NRG1 (IgNRG1beta2) containing an immunoglobulin-like domain which is probably essential for efficient interaction with ErbB receptors. PMID:17007820

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Subcellular Location

[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-1]: Secreted.

Protein Families

Neuregulin family

Tissue Specificity

Isoform alpha1 is expressed in brain and muscle. Isoform CRD is expressed in brain and spinal cord, but at very low level in muscle.

Database Links

UNIGENE: Xl.289

KEGG: xla:373595

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