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Recombinant Xenopus laevis Pituitary homeobox 2 (pitx2)

Recombinant Xenopus laevis Pituitary homeobox 2 (pitx2)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

pitx2

Purity

>85% (SDS-PAGE)

Target Names

pitx2

Uniprot NO.

Q9PWR3

Alternative Names

pitx2; ptx2; Pituitary homeobox 2; Homeobox protein PITX2; Paired-like homeodomain transcription factor 2; xPtx2

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-326

Target Protein Sequence

MNSMKEPLHL DHLAGSRVAA ASSHHHHHHH HQHQTVTLVS MASSLGQRSG ECKSRLEVHT ISDTSSPDTA DKDKSHQTKN EDSSTDDPSK KKRQRRQRTH FTSQQLQELE ATFQRNRYPD MSTREEIAVW TNLTEARVRV WFKNRRAKWR KRERNQQAEL CKNGFGPQFN GLMQPYDDMY PSYSYNNWAA KGLTSASLST KSFPFFNSMN VNPLSSQSMF SSPNSISSMS MSSGMVPSAV TGVPGSGLNS LNNLNNLSNP SLNTAVPTSA CPYAPPTPPY VYRDTCNSSL ASLRLKAKQH SSFGYATVQT PGSNLSACQY AVDRPV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May play an important role in development and maintenance of anterior structures and mediate left-right asymmetry. Could play a role at the interface of lateral plate signaling and heart and gut morphogenesis.

Gene References into Functions

ESR1 inhibits the expression of Pitx2 gene by binding to a left side-specific enhancer region in Pitx2 gene and recruiting histone deacetylase 1 to this region, leading to the suppression of Pitx2 gene in the left lateral plate mesoderm. PMID:24440151

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Subcellular Location

Nucleus.

Protein Families

Paired homeobox family, Bicoid subfamily

Database Links

UNIGENE: Xl.103

KEGG: xla:373586

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