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Recombinant Xenopus laevis Nuclear receptor subfamily 6 group A member 1 (nr6a1)

Recombinant Xenopus laevis Nuclear receptor subfamily 6 group A member 1 (nr6a1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

nr6a1

Uniprot NO.

P70033

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-435

Target Protein Sequence

MDTWEDDRVD QRACLICGDR ATGLHYGIIS CEGCKGFFKR SICNKRVYRC SRDKNCVMSR KQRNRCQYCR LLKCLQMGMN RKAIREDGMP GGRNKSIGPV QISDEEVERI MSGQEFEEEA NTSWSNNGDS DHSSPGNAVS ESNQPSPVST PSSSRSMELN GFSSLRDQYL GTPGPTHYQY LPHLFSFSAH PTIIPAQSRS LDPQSHTLIN QLLTAEDIEP LNTPMLIEDG YKVTQSELFA LLCRLADELL FRQITWVKKL PFFCDLSIKD YTCLLSTTWQ ELILLSSITT YSKQIFGDLT DVTSKYSPSE DELHRFSEDG MEVMERLIYL FRKFSQLKVS NEEYVCMKAI NFLNQDIQGI SSASQVEQLN KRYWYVCQDF TEYRYPHQPN RFPDLMMCLP EVRYIAGKLV NVPLEQLPLL FKAFLHSCKT IVTKE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Probable orphan nuclear receptor. Binds to a response element containing repeats of the motif 5'-AGGTCA-3'. Required for anterior-posterior patterning during organogenesis. Acts with chordin to play a role in patterning the midbrain-hindbrain. Isoform Em is required for integrin-mediated cell matrix interaction during neurulation and for the morphogenetic movements leading to formation of the neural tube. Also mediates the effect of retinoic acid on primary neurogenesis.

Gene References into Functions

evidence pesented that illustrates the function of germ cell nuclear factor in the early development of the CNS [GCNF] PMID:12676320

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Nuclear hormone receptor family, NR6 subfamily

Tissue Specificity

Transiently expressed in differentiating cells of all embryonic germ layers. Expressed in an anterior to posterior concentration gradient from late gastrula to midneurula stages. Shows a complicated spatio-temporal pattern of expression during neurulation

Database Links

UNIGENE: Xl.37734

KEGG: xla:399304

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