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Recombinant Xenopus laevis Nuclear receptor corepressor 1 (ncor1), partial

Recombinant Xenopus laevis Nuclear receptor corepressor 1 (ncor1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ncor1

Purity

>85% (SDS-PAGE)

Target Names

ncor1

Uniprot NO.

Q8QG78

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-2498

Target Protein Sequence

MSSSGYPPNQ GAFSTEQGRY SSHPVQYTFP SSRHQQEYSV SEYRTAHLEA SQLIQQQQLR RRPSLLSEFH PVSDRPQDRR SGYDQQYHSI SQNEHEALES KRPRLDQVSD SHYRLNPAMV LLVPTIQEGV RVQSEVKKEQ GLSSKHESSS SPLSGQPGDD QDASPSKLSK EELIQSMDRV DREIAKVEQQ ILKLKKKQQQ LEEEAAKPPE PEKPVSPPPV EQKHRSVVQI IYDENRKKAE EAHKFLEGLG PKVELPLYNQ PSDTKVYHEN IKTNQVMRKK LILFFKRRNH ARKLREQNIC QRYDQLMEAW EKKVDRIENN PRRKAKESKT REYYEKQFPE IRKQREQQER FQRVGQRGTG MSATIARSEH EISEIIDGLS EQENNEKQMR QLSVIPPMMF DAEQRRVKFI NTNGLMEDPM KVYKDRQFMN VWTDHEKEIF KEKFVRHPKN FGLIASYLER KNVSDCVLYY YLTKKNENLK SLVRRNYPKR RGRNQQQITR PSQEEKEIEK VEEEKADRND KKEDERREEE EKEEKEELRE GAKDKIDAVA EDGDEKDQSM PRGRKTANNQ GRRKGRVTRS MASEAAAANA VTTATTAPVT TTSTATTVAP VPVAPPPEEP TPPPPPQEQS LVDHGRNWGA IAKMVGSKSE SQCKNFYFNY KRRHNLDNLL QQHKQKSSRR PREERDVSQC DSIASTVSAQ EDDENEASNE EENPEDSEGA ENSSDTESAP SPSPAEAARL GDDSVDRTTS SVSMEAPPEQ DAASKPASDS SPSPIVENTK PPETQYAELK VKEEISTENE QTMEVEERSQ SAELKSALNL QVQTKAEPYE TEAKPTESTT QVKTEVDSKE DDSMERLMDR AEAADMGYAP PQNISQARQE SQPDNDSSAT CSADEEVDGE PDRPRMYSFG SRPSLLNQAG TFLKQGPMDL QQLQHRAAVI PPMTSCSPCN LTTGTAIAAS NFSMYQRHLY ENSLLEEQRQ RQEQLTLENR MSASPGNMSK SPNMDWEGKS VYMPYTEVKH PFEHEAQMQN VARSVSPYRL SPRDVGRVSP QVDMNPSRYC VPPVLQPAPH QVITSLSDSA RLPVTRPTRP PPPLIPSSKT SATSSDKPSF ITGGSISQGT PGTYLASLSQ PYSQETLKPS VGSISLGLPR QHESTKIGCV TYIKQEEFPS RGQSSQPEGL LVRAQHEGVV RGSMAAIQEG SIARGTPATK VPLEAVSTLR GSITQGTPAL SQSGIAADVL LKSTITRLAA EDIGSPERCR EDTSAKGHVI YEGKSGHIVS YDTIKNMREG TRSPRTAPEV ALKRAYDTME GNIKQAMSVR EAAVSGPMEG LICRTLPKGS PHPELKDRQV LSGSIMKGTP RTTSDNFDDG LKYAKQIKLE SPPIRSFEGA ISKGKPYEGV TTIKELGRSI HEIPRQDLVS QESRKTPESS RQIMEGSISQ GTPIKYESTS GQSAIKHNVK SLITGPSNLS WGVPQMDNMP ENLKMGERSK HEDTKSSDAI RSRHTSVVSS GPSVLRSTLH EASKSQLSPG IYEDNNARRT PVNYPSPMSR SSPMARSAEG CLTPSKSSSH ERKSTLTPTQ RESIVVKSPV PGVDPSAAHS PFDTHLRSAP PGDVYRAHLP PHLDPALQFH RPLDPAAAAY LFQRQLSPTP GYPSQYQLYA MENTRQTILN DYITSQQMQV NLRPDVARGL SPRDQGLGIP YPGARGIIDL TNMPPAILVP HPGGTSTPPM DRITYIPGTQ LAFPPRPYNP ASMSPGHPAH LANSVSAERE RERERERERD REREKEQRER ESDRERERDR LAHAAAAAAA ASAPSEHYLR PVSEQPSRPS SRPSSHGYVR SPSPSVRAQE SIMQQRPSIF LGTNGKSVIT PLDAAQFRIM PPTPGAASIT QGIPASRYST AADALAALVD AATSAPQMEV AKPKESKNDS ARSEENLSRR NALEQQQQID CERRVMQSPY TSSSFSSSKS QSQPSSAVYS EAGKERTAHT KSRYVEELRM RGKTTITAAN FIDVIITQQI ASDKDGRERN SQSSDASSSH SSHRYEAPRE TIEVISPANS PVQEKESYPQ EMPKSSQTET GEGSRKYDGQ PNRYRQQQES PPQQTIPGHV PQTHRLITLA DHICHIITQD FARNQPVNQP LQQPPASTFQ STNPTSTAVR TKASSRFSPE SQVQPMHSPR PASRVSPENI PDKPRGRPGK SPDRGHISEP YEPISPPQAP MLHTKQDNMM LLSQRQEPPE QRNDSRSPGN INYLPSFFTK LENTSPMVMY KKQEIFRKLN SSGGGDSDMA AAQPGTEIFN LPAVTTSGAI SSRGHSFADP ASNLGLEDII RKALMGNFDD KSEDHGVLVG VPQGNQSGTP NSEARREEAN PSPNSGGGTH KQKLISKYGS RKTKSPISGS QTYLGAERPS SVSSVHSEGD YRQASAWAWE DRPSSTGSTQ FPYNPLTMGM LNSTPPSSMS CIPTSMTQTS AHQQSRIWER EPAPLLSEQY ETLSDSDE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Mediates transcriptional repression by certain nuclear receptors. Participates in complexes which promote histone deacetylation and the formation of repressive chromatin structures which may impede access by the basal transcription machinery. In association with hdac3, may play a role in the regulation of the circadian clock.

Gene References into Functions

Data provide in vivo evidence for targeted recruitment of N-CoR/SMRT-TBLR1 complexes by unliganded thyroid hormone receptors in transcriptional repression during vertebrate development PMID:15060155

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Subcellular Location

Nucleus.

Protein Families

N-CoR nuclear receptor corepressors family

Database Links

UNIGENE: Xl.2761

KEGG: xla:398304

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