Home
Product
Protein
Recombinant Proteins
Recombinant Xenopus laevis Methyltransferase-like protein 14 (mettl14)

Recombinant Xenopus laevis Methyltransferase-like protein 14 (mettl14)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

mettl14

Purity

>85% (SDS-PAGE)

Target Names

mettl14

Uniprot NO.

Q6NU56

Alternative Names

mettl14N6-adenosine-methyltransferase non-catalytic subunit; Methyltransferase-like protein 14

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-456

Target Protein Sequence

MNSRLQEIRA RQTLRRKLLA QQLGAESADS IGAVLNSKDE QREIAETRET SRASYDTSAA VSKRKLPEEG KADEEVVQEC KDSVEPQKEE ENLPYREEIY KDSSTFLKGT QSLNPHNDYC QHFVDTGHRP QNFIRDVGLA DRFEEYPKLR ELIRLKDELI AKSNTPPMYL QADLETFDLR ELKSEFDVIL LEPPLEEYFR ETGIAANEKW WTWEDIMKLD IEGIAGSRAF VFLWCGSGEG LDFGRMCLRK WGFRRSEDIC WIKTNKDNPG KTKTLDPKAI FQRTKEHCLM GIKGTVHRST DGDFIHANVD IDLIITEEPE IGNIEKPVEI FHIIEHFCLG RRRLHLFGRD STIRPGWLTV GPTLTNSNFN SETYASYFNT PNSPLTGCTE EIERLRPKTP PPKSDRGFGA SRGGGRGGAS AGRGERGRER NRGSFRGDRG NFRGRGGPHR GVFAPR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

Subcellular Location

Nucleus.

Protein Families

MT-A70-like family

Database Links

UNIGENE: Xl.7634

KEGG: xla:414467

Promotions