Recombinant Xenopus laevis Hypoxia-inducible factor 1-alpha (hif1a), partial

Product Details

Abbreviation
hif1a
Purity
>85% (SDS-PAGE)
Target Names
hif1a
Uniprot NO.
Species
Xenopus laevis (African clawed frog)
Source
Yeast
Expression Region
1-805
Target Protein Sequence
MEGSVVVSEK KRISSERRKE KSRDAARCRR SNESEVFYEL SHELPLPHNV SSHLDKASIM RLDHQLPAVE KVADAGDLDG ETELDKQLNC FYLKALEGFV LVLTEEGDMI YLSENVNKCM GLTQFELTGH SVFDFTHPCD HEELREMLTF RNGPAKKRKR TNHREKFLPS YEMYINQSWK NREYKVSHME GPSLYRTHAC IYDNANNQNH CGYKKPPMTC MVVICEPIPH PSNIEFPLDS KTFLSRHSLD MKFSYCDERV TELVGYEPDE LLGRSVYEYY HALDSDHLTK PNYNMFTKGQ VTTGQYRMLA KKGGYVWVET QATVIYNSKN SQPQCIVCVN YVLSEVVEKD LILSLGQTAS VLIPVESQEI KMPEIFTELN EENNSECLFD KLKQEPESLT VLAPDAGDEI IPLDFSSGDS DKPYEDVPLY NDVMLHSTSN KLESTPITPL PAPEMPKPLR SNVDPALNRE VVIKMESNPR TTCASIHHST AIQARQPFRY QFQSEPSTEP NTPEYCFDVD SEMASEFKLD LVEKLFAIDT EAKAPFYYPG NDLDLEMLAP YIPMDDDFQL RTFDQLSSLE CDSSIPQTLG SMTTLFHQSL SPSTSDFKPE DAMSDLKTII QSPVHMMKES TSAPVSPYNG NRSRTSSPVR PAKAVVDKTE KSRPGTPNLP VPLNKRCTIL DEELNPKMIC FTQCTAEKRK MESDGPLFQA IGIGTLFQTN VDPGPNSSLQ WKRVKGSDSE RLSSAEQRTI LLLSTDMASQ LLGQSFDGTV LPQLTGYDCE VNAPVHGTRN LLQGEELLRA LDQAN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.
Subcellular Location
Cytoplasm. Nucleus. Nucleus speckle.
Database Links

UNIGENE: Xl.4589

KEGG: xla:100337573

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