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Recombinant Xenopus laevis Homeobox protein DLL-4 (dll4)

Recombinant Xenopus laevis Homeobox protein DLL-4 (dll4)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

dll4

Uniprot NO.

P53775

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-285

Target Protein Sequence

MTGVFDSLAA DMHSNHMPSS SYHSLHKSQE SPTLPVSTAT DSSYYTNQQQ QQHCGAVSPY GQLGSYQFHG AAINGISYST KSYDLSYTGS YSSYGPYGTS PSPPHNDQEK EDCEPEVRMV NGKPKKVRKP RTIYSSFQLA ALQRRFQKTQ YLALPERAEL AASLGVTQTQ VKIWFQNRRS KFKKMWKSGE IPSDQLPVGS ESSPCSSPSA STATWDFGPH QRLQGATNGS ALQSSNSASS PSPFLSNYSW YQTSNSAPHL QSNPLLQQHH LHHHPPAPIS AGTIF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Subcellular Location

Nucleus.

Protein Families

Distal-less homeobox family

Tissue Specificity

Expression restricted to anterior ectodermal derivatives, namely the ventral forebrain, the cranial neural crest and the cement gland. Also expressed in the developing eye.

Database Links

UNIGENE: Xl.721

KEGG: xla:399264

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