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Recombinant Xenopus laevis Diablo homolog, mitochondrial (diablo)

Recombinant Xenopus laevis Diablo homolog, mitochondrial (diablo)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

diablo

Uniprot NO.

A4GZV0

Alternative Names

diablo; smacDiablo homolog; mitochondrial; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac protein; XSmac

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

58-244

Target Protein Sequence

EPT LSSESLIKRA ASLVADSSST FLSQTTYALV ESLTEYTTAV YTLISLQQKY SSLLDKINSN EESAIWQVII GARVQINQLK EQYMKYESSW QRAVSLSEMA AEAAYQSGAD QASMTVRNHI QIVQTQVQGA RDQAHMAEVQ LAASQTEEIK RTITEDKGNP PSGGSPRNSL SEEEDIPEAY LRED
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Promotes apoptosis.

Gene References into Functions

hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondria before significant amounts of cytochrome c are released to promote caspase-3 activation PMID:25866890
Identification of the third vertebrate homologue of Smac/DIABLO. PMID:17336467

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Subcellular Location

Mitochondrion.

Database Links

UNIGENE: Xl.76004

KEGG: xla:100049147

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