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Recombinant Xenopus laevis Casein kinase I isoform delta (csnk1d)

Recombinant Xenopus laevis Casein kinase I isoform delta (csnk1d)

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MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

csnk1d

Purity

>85% (SDS-PAGE)

Target Names

csnk1d

Uniprot NO.

Q5BP74

Alternative Names

csnk1d; Casein kinase I isoform delta; CKI-delta; CKId; EC 2.7.11.1

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

1-415

Target Protein Sequence

MELRVGNRYR LGRKIGSGSF GDIYLGTDIA ASEEVAIKLE CVKTKHPQLH IESKIYKMMQ GGVGIPTIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFAT YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGASRA AEDAERERRE REERLRHTRN PAVRGLPSTA SGRLRGTQEV TPSTPLTPTS HTANTSPRPV SGMERERKVS MRLHRGAPVN VSSSDLTSRQ DTSRMSTSQI PSRVTSSGLP STVHR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Isoform 1 can phosphorylate a large number of proteins. Isoform 2 has no kinase activity. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating per1 and per2, which may lead to their degradation. Participates in wnt signaling.

Gene References into Functions

The results demonstrate a high degree of evolutionary conservation of fly and vertebrate CKIdelta and of the functions affected by their period-shortening mutations. PMID:18957703

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Subcellular Location

Cytoplasm. Nucleus. Note=Isoform 1 is found in the cytoplasm and the nucleus; isoform 2 is found in the cytoplasm.

Protein Families

Protein kinase superfamily

Tissue Specificity

Detected in retina photoreceptor cells.

Database Links

UNIGENE: Xl.1636

KEGG: xla:380361

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