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Recombinant Xenopus laevis Bone morphogenetic protein 4 (bmp4)

Recombinant Xenopus laevis Bone morphogenetic protein 4 (bmp4)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

bmp4

Uniprot NO.

P30885

Alternative Names

bmp4; dvr-4Bone morphogenetic protein 4; BMP-4

Species

Xenopus laevis (African clawed frog)

Source

Yeast

Expression Region

288-401

Target Protein Sequence

SPK QQRPRKKNKH CRRHSLYVDF SDVGWNDWIV APPGYQAFYC HGDCPFPLAD HLNSTNHAIV QTLVNSVNSS IPKACCVPTE LSAISMLYLD EYDKVVLKNY QEMVVEGCGC R
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Posterior-ventralizing factor in Xenopus mesoderm induction. Induces posteroventral mesoderm and counteracts dorsalizing signals such as activin.

Gene References into Functions

Data indicate that bone morphogenetic protein (BMP) signaling is essential for erythroid differentiation, and in the absence of BMP signaling, precursor cells adopt an endothelial cell (EC) fate. PMID:24100450
limits homeobox gene expression in the organiser/non-organiser direction PMID:14729483
X-epilectin expression is down-regulated by Noggin and tBR and that this effect is inhibited by BMP4 over-expression PMID:15602698
BMP4-dependent expression of Xenopus Grainyhead-like 1 has a critical role in epidermal differentiation PMID:15705857
XBP1 interacts with BMP-4 and Xvent-2B promoters. PMID:16278078
connective tissue-specific expression of BMP-4 mRNA is up-regulated by sonic hedgehog (Shh) PMID:17016847
An intermediate level of BMP4 signaling is required to induce neural plate border fates. PMID:18191829
BMP4 inhibits Tolloid enzyme activity noncompetitively PMID:19884260