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Recombinant Varicella-zoster virus Major DNA-binding protein (DBP), partial

Recombinant Varicella-zoster virus Major DNA-binding protein (DBP), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

DBP

Purity

>85% (SDS-PAGE)

Target Names

DBP

Uniprot NO.

Q4JQU6

Species

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Source

Yeast

Expression Region

1-1199

Target Protein Sequence

MENTQKTVTV PTGPLGYVYA CRVEDLDLEE ISFLAARSTD SDLALLPLMR NLTVEKTFTS SLAVVSGART TGLAGAGITL KLTTSHFYPS VFVFHGGKHV LPSSAAPNLT RACNAARERF GFSRCQGPPV DGAVETTGAE ICTRLGLEPE NTILYLVVTA LFKEAVFMCN VFLHYGGLDI VHINHGDVIR IPLFPVQLFM PDVNRLVPDP FNTHHRSIGE GFVYPTPFYN TGLCHLIHDC VIAPMAVALR VRNVTAVARG AAHLAFDENH EGAVLPPDIT YTYFQSSSSG TTTARGARRN DVNSTSKPSP SGGFERRLAS IMAADTALHA EVIFNTGIYE ETPTDIKEWP MFIGMEGTLP RLNALGSYTA RVAGVIGAMV FSPNSALYLT EVEDSGMTEA KDGGPGPSFN RFYQFAGPHL AANPQTDRDG HVLSSQSTGS SNTEFSVDYL ALICGFGAPL LARLLFYLER CDAGAFTGGH GDALKYVTGT FDSEIPCSLC EKHTRPVCAH TTVHRLRQRM PRFGQATRQP IGVFGTMNSQ YSDCDPLGNY APYLILRKPG DQTEAAKATM QDTYRATLER LFIDLEQERL LDRGAPCSSE GLSSVIVDHP TFRRILDTLR ARIEQTTTQF MKVLVETRDY KIREGLSEAT HSMALTFDPY SGAFCPITNF LVKRTHLAVV QDLALSQCHC VFYGQQVEGR NFRNQFQPVL RRRFVDLFNG GFISTRSITV TLSEGPVSAP NPTLGQDAPA GRTFDGDLAR VSVEVIRDIR VKNRVVFSGN CTNLSEAARA RLVGLASAYQ RQEKRVDMLH GALGFLLKQF HGLLFPRGMP PNSKSPNPQW FWTLLQRNQM PADKLTHEEI TTIAAVKRFT EEYAALNFIN LPPTCIGELA QFYMANLILK YCDHSQYLIN TLTSIITGAR RPRDPSSVLH WIRKDVTSAA DIETQAKALL EKTENLPELW TTAFTSTHLV RAAMNQRPMV VLGISISKYH GAAGNNRVFQ AGNWSGLNGG KNVCPLFTFD RTRRFIITCP RGGFICPVTG PSSGNRETTL SDQVRGIIVS GGAMVQLAIY ATVVRAVGAR AQHMAFDDWL SLTDDEFLAR DLEELHDQII QTLETPWTVE GALEAVKILD EKTTAGDGET PTNLAFNFDS CEPSHDTTSN VLNISGSTVP GLKRPPEDDE LFDLSGIPIK HGNITMEMI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.

Subcellular Location

Host nucleus.

Protein Families

Herpesviridae major DNA-binding protein family

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