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Recombinant Solanum lycopersicum DNA damage-binding protein 1 (DDB1), partial

Recombinant Solanum lycopersicum DNA damage-binding protein 1 (DDB1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

DDB1

Purity

>85% (SDS-PAGE)

Target Names

DDB1

Uniprot NO.

Q6QNU4

Alternative Names

DDB1; hp1DNA damage-binding protein 1; High pigmentation protein 1; UV-damaged DNA-binding protein 1

Species

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Source

Yeast

Expression Region

1-1090

Target Protein Sequence

MSVWNYVVTA HKPTNVTHSC VGNFTGPQEL NLIIAKCTRI EIHLLTPQGL QPMLDVPIYG RIATLELFRP HGETQDLLFI ATERYKFCVL QWDTEASEVI TRAMGDVSDR IGRPTDNGQI GIIDPDCRLI GLHLYDGLFK VIPFDNKGQL KEAFNIRLEE LQVLDIKFLY GCPKPTIVVL YQDNKDARHV KTYEVSLKDK DFIEGPWAQN NLDNGASLLI PVPPPLCGVL IIGEETIVYC SASAFKAIPI RPSITRAYGR VDADGSRYLL GDHNGLLHLL VITHEKEKVT GLKIELLGET SIASTISYLD NAFVFIGSSY GDSQLVKLNL QPDTKGSYVE VLERYVNLGP IVDFCVVDLE RQGQGQVVTC SGAYKDGSLR IVRNGIGINE QASVELQGIK GMWSLRSATD DPYDTFLVVS FISETRVLAM NLEDELEETE IEGFNSQVQT LFCHDAVYNQ LVQVTSNSVR LVSSTSRDLK NEWFAPVGYS VNVATANATQ VLLATGGGHL VYLEIGDGVL NEVKYAKLDY DISCLDINPI GENPNYSNIA AVGMWTDISV RIYSLPDLNL ITKEQLGGEI IPRSVLMCSF EGISYLLCAL GDGHLLNFVL SMSTGELTDR KKVSLGTQPI TLRTFSSKDT THVFAASDRP TVIYSSNKKL LYSNVNLKEV SHMCPFNVAA FPDSLAIAKE GELTIGTIDE IQKLHIRSIP LGEHARRISH QEQTRTFALC SVKYTQSNAD DPEMHFVRLL DDQTFEFIST YPLDQFEYGC SILSCSFSDD SNVYYCIGTA YVMPEENEPT KGRILVFIVE DGKLQLIAEK ETKGAVYSLN AFNGKLLAAI NQKIQLYKWA SREDGGSREL QTECGHHGHI LALYVQTRGD FIVVGDLMKS ISLLIFKHEE GAIEERARDY NANWMSAVEI LDDDIYLGAE NNFNLFTVRK NSEGATDEER SRLEVVGEYH LGEFVNRFRH GSLVMRLPDS DVGQIPTVIF GTVNGVIGVI ASLPHDQYLF LEKLQTNLRK VIKGVGGLSH EQWRSFYNEK KTVDAKNFLD GDLIESFLDL SRNRMEEISK AMSVPVEELM KRVEELTRLH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Component of light signal transduction machinery. Involved in fruit pigmentation and fruit nutritional quality. Acts as a negative regulator of fruit pigmentation. Probably acts by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes. Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5.

Gene References into Functions

the physical interaction of SlMBD5 with the CUL4-DDB1-DET1 complex component may affect its binding activity to methylated DNA and subsequently attenuate its transcription activation of downstream genes. PMID:26551231
five transgenic lines constitutively overexpressing normal DDB1 in hp-1 mutant plants were analysed PMID:20566564
In hp1 mutant pericarp tissue at early developmental stage, an apparent expression alteration was found in several regulators directly involved in plastid division and development. PMID:23948801
results suggest DDB1 plays an important role in regulation of the epigenetic state of genes involved in organogenesis PMID:22927934
HP1/DDB1 may function through interaction with the salicylic acid-regulated PAMP-triggered immunity pathway in resistance against Agrobacterium infection. PMID:21726402