Recombinant Sheep Transcription factor SOX-2 (SOX2)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
SOX2
Uniprot NO.
Species
Ovis aries (Sheep)
Source
Yeast
Expression Region
1-320
Target Protein Sequence
MYNMMETELK PPGPQQTSGG GGGGGGNSTA AAAGGNQKNS PDRVKRPMNA FMVWSRGQRR KMAQENPKMH NSEISKRLGA EWKLLSETEK RPFIDEAKRL RALHMKEHPD YKYRPRRKTK TLMKKDKYTL PGGLLAPGGN SMASGVGVGA GLGAGVNQRM DSYAHMNGWS NGSYSMMQDQ LGYPQHPGLN AHGAAQMQPM HRYDVSALQY NSMTSSQTYM NGSPTYSMSY SQQGTPGMAL GSMGSVVKSE ASSSPPVVTS SSHSRAPCQA GDLRDMISMY LPGAEVPEPA APSRLHMSQH YQSGPVPGTA INGTLPLSHM
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. May function as a switch in neuronal development.
Subcellular Location
Nucleus.
Database Links
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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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