Recombinant Sheep Osteopontin (SPP1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

SPP1

Purity

>85% (SDS-PAGE)

Target Names

SPP1

Uniprot NO.

Q9XSY9

Species

Ovis aries (Sheep)

Source

Yeast

Expression Region

17-278

Target Protein Sequence

LPVK PTSSGSSEEK QLNNKYPDAV ATWLKPDPSQ KQTFLEPQNS VSSEETDDNK QNTLPSKSNE SPEQTDDLDD DDENSQEVNS DDSDDAETPD DSDHSNESHH SDESDEADFP TDIPTIAVFT PPFPTESTND GRGDSVAYGL KSKSKKFRRS NVESPDATEE DFTSHIESEE MHDAPKKTSQ LTDHSEETNS DELPKELTPK AKEESKHSNR IESQENSKLS QEFHSLEDKL DLDHKSEEDK RLKIRISHEL DSVSSEVN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.

Gene References into Functions

hese results suggested that the expression of OPN might be closely related to spermatogenesis and spermatozoa function in Hu sheep. This will be helpful for us to understand how OPN regulate the high reproductive capacity in Hu sheep. PMID:27514848
examined the interaction of estrogen receptor-alpha (ERalpha), estrogen receptor-related receptor-alpha (ERRalpha), and stone matrix protein osteopontin (OPN) in a hyperoxaluric model PMID:21186342

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Subcellular Location

Secreted.

Protein Families

Osteopontin family

Database Links

UNIGENE: Oar.14771

KEGG: oas:443058

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