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Recombinant Schizosaccharomyces pombe Cullin-1 (cul1), partial

Recombinant Schizosaccharomyces pombe Cullin-1 (cul1), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

cul1

Uniprot NO.

O13790

Alternative Names

cul1; pcu1; SPAC17G6.12Cullin-1; Cul-1; Cell division control 53 homolog

Species

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Source

Yeast

Expression Region

1-767

Target Protein Sequence

MTTLNTNDKD LPIVKKYDSL NGTWDFLKTG VSQIFERLDE GMTITKYMEL YTAIHNYCAD ASKTITVDNF NDQTANVLGE ALYNNLVLYL EEYLARLRKE CISQTNHEEQ LAAYAKYWTR FTTSARFINH LFGYLNRYWV KLKNRFTETL VYDIYTLCLV SWHHHVFSHI RDSLLQNLLY MFTKKRLYEP TDMKYVEVCV DSITSLSFDK TDMTKPNLSS YKTFFETNFI ENTKNFYAKE SSEYLASHSI TDYLKKAEIR LAEEEELVRL YLHESTLKPL LEATEDVLIA QHEEVLHNDF ARMLDQNCSE DIIRMYRLMS RTPNGLQPLR QTFEEFVKRS GFAAVAKIVP QVGGEADVDP KEYMEMLLST YKASKELVNT AFHGDTDFTK SLDTAFRELV NRNVVCQRSS SRSPELLAKY ADSILRKSNK NVDIDDVEDC LSSIIIIFRY VEDKDVFQNF YTKLLAKRLV NGTSNSQDAE SSMLSKLKEV CGFEYTSKLQ RMFQDISLSQ EITEAFWQLP QSRAGNIDFS ALVLGTSFWP LSPNNVNFHL PEELVPLYEG FQNYYYSCHN GRKLSWLFHL SKGEIKARIN PQTNVTYVFQ VSTYQMGVLL LYNHRDSYTY EELAKITGLS TDFLTGILNI FLKAKVLLLG DNDKLGDPNS TYKINENFRM KKIRVQLNLP IRSEQKQESL ETHKTIEEDR KLLLQSAIVR IMKARRTLKH VVLVKETIDQ IKSRFTPKVS DIKQCIDMLI EKEYLERQGR DEYIYLA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2.

Subcellular Location

Cytoplasm.

Protein Families

Cullin family

Database Links

KEGG: spo:SPAC17G6.12

STRING: 4896.SPAC17G6.12.1

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