Recombinant Schizosaccharomyces pombe Autophagy protein 13 (atg13), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
atg13
Uniprot NO.
Alternative Names
atg13; mug78; SPAC4F10.07cAutophagy protein 13; Meiotically up-regulated gene 78 protein
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Source
Yeast
Expression Region
1-758
Target Protein Sequence
MPRLNTQLPR MYSAPPGHSK AVSTELNKDL SSVGGRSAKL GQVIHHCFYK TGLIILESRL NVFGTSRPRE SSKNNKWFNL EIVETELYAE QFKIWKNIEL SPSRKIPPMV LHTYLDISDL SKNQTLSVSD GTHSHAINFN NMSTMKIVLE RWIVNLDGEA LSTPLELAVL YKKLVVLFRS LYTYTHLMPL WKLKSKIHKL RAHGTSLKVG CALSTDDVLS NDFLPISAPI SSSLGSSIAT FSFSPVGTPA GDFRISVQYR KNCHFEVHDS DALLSNQLLS ADKHQLAASN NSQDFEDGKQ YDQPPPSFAT RLAKQSDPNS LLQSEIQHLA SIESITAQAA PLVTIHPFKS PSLSASPGSN FDNMSISPKV AVNRYIHRGP SATSLNKFSM ISDAASKSRA KLPPLTSGSL KLNTLDISNT PNLRRFSSSF GPRERKESFS SRNRLPLVNH PIRSIFKHNV SENPITDHSE HAVYDSEFAS KDDLSGFIQL LDSHAHHLNA SEGSKSSGSF PGKVQTLTSG ISPVAHPHNS LGSSNEIFDI DTYNHSIDNS GSRFTEAVKH NLGNSSHSIM RHHTLGTLRS RPSFSEKSTF PAPLTSISQA STFQGDNRSP STVIPHTQTE VPSANDTSKQ LASLHDMRKS QSPICARSAT SAGLPRFEYH TSLSKSLEHS STPASLQATK TPSPSFVLEP GIPQEYKKHF DNLSEERRQC LTPSTPTYEY YNEHNPNYDD DLLFTMTDMT LEPHDVSAIR LGSPKSDD
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Autophagy functions to supply nitrogen and is activated when cells cannot access exogenous nitrogen, thus ensuring that they can adapt and subsequently propagate. Finally, atg13 is also required for glycogen storage during stationary phase and has a role in meiosis and sporulation.
Gene References into Functions
  1. The study reports the crystal structure of the fission yeast Atg101-Atg13 complex. PMID:26030876

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Subcellular Location
Cytoplasm. Preautophagosomal structure.
Protein Families
ATG13 family, Fungi subfamily
Database Links
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