Recombinant Saccharomyces cerevisiae Peroxisome proliferation transcriptional regulator (PIP2), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
PIP2
Uniprot NO.
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Source
Yeast
Expression Region
1-996
Target Protein Sequence
MYFTDESSPA MNRVGKKRNR LSFVCQACRK AKTKCDQEKP RCGRCTKQNL FCIYDVARQA APRNPNKDAT IARLKKEIRY WRNKTVDLTQ EKKDFYTALK RPTEELAARR TCKSLQENSF PISLYKTHPR LIMTKVMKRE INPLSEKYLI FQDTFLKTLI ASVLLSCSRN SMIPALNADI SRSRTQPCVK NNVVKMREVL LKNSKYESQR KSINEFTDRL LQRKNPEEQI AVNKVISLLY SNRESSYLED TCPTENDYSD LLKGYINEIE KTLPPKAIIE QYLSHFFEHI FHLIPFASKE MLEESIHTTV QYNELGEVRL SMGTTLIRNK MENLCILLLI LRIAYISLTF IEDKIEDYSP YITKEMLEQY PIQSEVIFLA QQILASENWC ACANENTISC LLYIWCAFVF SPTEGDFLLE QPSDVIINLV ILIGTSIGLH RDPSDFPALN HPEASDKRLL NLRRIQWLSI ISMATLESSL KGRLLVSPLS MIDLFIDVRD PNCVEIYKKR VKKDLTGSES DEQLLEIHEI FFHRAQLALF LSDLNNITIS YSGSVPMDTL ETLRVKANEL LKNKFQLRSV DINIYDEEKT FQKLTFNSIL NSISLSGQIL GKLMMLRASI ALMLYFETLA MERSECLSFF YKYFFQCCAD TISLIRFFFL YFNGSYEKVL SSLVCFITTK VIQLAVPTTM FTLLVIIMRV ELAKNMLLVK CNECNARGDI SDLPEIKEKI KSLDTIKENF ERLLLEVYLL ASQNLRFKYF YIFKMLTLFD VFIQRLRKGQ LFSGLFVKVD KDLTTKKIAT MLELTLGINL DKSDHLIDRL KGKNLTVNFT LDQLYQIIKE FDRIKNIGVA DPQNSLNPSK PNMKDNTPTI ELLLNSSVEN ESVPPYSSSN DPTNVGNAST YSLAHNISNQ NNEENMPPSI GSSESNRAAP NLNFMPINNN YNNSGSNINN NDNVKLPSNF KNYYDPPMSS LDISMDVPDI FGSLDFFDYD LLFQND
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
The PIP2-OAF1 heterodimer acts as a transcriptional activator to induce the transcription of genes encoding proteins involved in fatty acid beta-oxidation, a response called oleic acid induction, when cells grow on fatty acids as sole carbon source. Recognizes and binds to the oleate response element (ORE) (or peroxisome box), two inverted CGG triplets spaced by 14 to 18 intervening nucleotides, in the promoter region of a number of genes (such as CTA1, FOX1 to FOX3, FAA2, PAS8, PAS10, etc.) for peroxisomal proteins. Activity is inhibited by OAF1 under non-inducing conditions. Activity is repressed by glucose.
Gene References into Functions
  1. In the absence of Pip2, Oaf1 may form homodimers. PMID:18671944

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Subcellular Location
Nucleus.
Database Links

KEGG: sce:YOR363C

STRING: 4932.YOR363C

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