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Recombinant Saccharomyces cerevisiae Nitrogen permease regulator 2 (NPR2), partial

Recombinant Saccharomyces cerevisiae Nitrogen permease regulator 2 (NPR2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

NPR2

Uniprot NO.

P39923

Alternative Names

NPR2; YEL062WNitrogen permease regulator 2

Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Source

Yeast

Expression Region

1-615

Target Protein Sequence

MLSYFQGFVP IHTIFYSVFH PTEGSKIKYE FPPNNLKNHG INFNTFKNYI IPKPILCHKL ITFKYGTYRI VCYPVTINSP IYARNFFSFN FVFVFPYDCE TSPYEPAITR LGKMFKVLEE QNQLLSKSER DPVFFDLKVL ENSTTTPSTA GPSSTPNPSS NTTPTHPTSE KDTKDMRSSR YSDLIKDLGL PQSAFSIQDL LMRIFQDLNN YSECLIPIDE GNAVDIKIFP LLRPPTTCVS LEDVPLSSVN LKKIIDVNWD PTMMSIVPYI DGLNSIAKIS KLSNSDPGLV IECIRHLIYY KCVTLSDIFQ FSNIYAPSSL IRNFLTDPLM ASDCQSYVTF PEVSKISNLP LNKSLGSGDQ DSPSFSVRRK SKSSSIPSNP DSRTTSFSST SRVSQNSSLN SSFSSIYKDW RQSQTSCSSS NIHVINNRNR FLPTRSCLFD LYRSLSQGQT LKTWYESKYM ILKENNIDIR RFITFGLEKR IIYRCYSFPV MINAGSREPK EMTPIITKDL VNNDKLLEKR NHNHLLSATG SRNTAQSGNL KPERPSKVSF EMQRVSSLAT GKSTMPKLSD EEEGILEESI RNAETFDKIC VLLSKPKLEV ESYLNELGEF KVINS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases. May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum. Involved in cell kill provoked by cisplatin and doxorubicin.

Gene References into Functions

These data revealed the metabolic basis by which the Npr2 complex regulates cellular homeostasis and demonstrated a key function for TORC1 in regulating the synthesis and utilization of glutamine as a nitrogen source. PMID:25515537

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Subcellular Location

Vacuole membrane; Peripheral membrane protein.

Protein Families

NPR2 family

Database Links

KEGG: sce:YEL062W

STRING: 4932.YEL062W

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